Hyperleukocytosis in Acute Myeloid Leukemia: Considerations for Inpatient Diagnosis and Management

被引:0
作者
Wheatley, Tia T. [1 ]
Castiglione, Haley Foster [2 ]
Phong, Kenneth [2 ]
Yoon, Monica [2 ]
机构
[1] Ronald Reagan UCLA Med Ctr, Hematol Oncol & Cellular Therapy, Los Angeles, CA 90095 USA
[2] Ronald Reagan UCLA Med Ctr, Hematol Oncol & Bone Marrow Transplant Unit, Los Angeles, CA USA
关键词
hyperleukocytosis; leukostasis; acute myeloid leukemia; tumor lysis syndrome;
D O I
10.1188/23.CJON.589-593
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Hyperleukocytosis, a white blood cell count greater than 100,000/mcl, can be associated with the following three primary oncologic emergencies: leukostasis, disseminated intravascular coagulation, and tumor lysis syndrome. These complications significantly increase a patient's risk of morbidity and mortality. Therefore, timely evidence-based interventions ensure patient safety. This article provides clinical evidence and guidelines for advanced practice nurses working in hematology-oncology to support diagnostic workup and management of hyperleukocytosis in patients with acute myeloid leukemia. A patient case study demonstrates key concepts.
引用
收藏
页码:589 / 593
页数:5
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