Results of surgical treatment of lymph node metastases in patients with cutaneous squamous cell carcinoma of the head and neck

被引:0
作者
Leon, Xavier [1 ,2 ]
Lopez, Susana [3 ]
Perez, Maria [3 ]
Valero, Cristina [1 ]
Holgado, Anna [1 ]
Quer, Miquel [1 ,2 ]
Vega, Carmen [3 ]
机构
[1] Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Serv Otorrinolaringol, Barcelona, Spain
[2] Ctr Invest Biomed Red Bioingn Biomat & Nanomed CIB, Madrid, Spain
[3] Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Serv Cirugia Plast, Barcelona, Spain
来源
ACTA OTORRINOLARINGOLOGICA ESPANOLA | 2024年 / 75卷 / 03期
关键词
Cutaneous squamous cell carcinoma; Head and neck; Lymph node metastases; Parotidectomy; Neck dissection; Extracapsular spread; Prognostic classification; O'Brien; SPREAD; CANCER; PROGNOSIS; OUTCOMES; SURGERY; SYSTEM;
D O I
10.1016/j.otorri.2023.07.007
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Introduction: Out of all cutaneous squamous cell carcinomas originating in the head and neck (HNCSCC), 2%-4% are associated with parotid or cervical lymph node metastasis. The aim of this study is to analyse the prognostic factors of patients with HNCSCC with lymph node involvement treated surgically. Additionally, we aim to compare the prognostic capacity of the classification of these patients according to the 8th edition of the TNM, and an alternative classification proposed by O'Brien et al. Patients and methods: Retrospective review of 65 patients with HNCSCC with lymph node metastasis treated surgically during the period 2000-2020. Results: During the study period we carried out 13 neck dissections and 52 parotidectomies + neck dissection in patients with lymph node metastases from a HNCSCC. The great majority of patients (89.2%) received post -operative radiotherapy. The 5 year disease -specific survival was 69.9%, and the overall survival it was 42.8%. The classification proposed by O'Brien et al., based on the parotid or cervical location of the lymph node metastases, and the size and number of the metastatic lymph nodes, had a better prognostic capacity than the TNM classification. Conclusions: The surgical treatment of lymph node metastases in patients with HNCSCC achieved a high disease control. The classification based on the location, size and number of lymph node metastases proposed by O'Brien et al. had better prognostic capacity than the TNM classification. (c) 2023 Sociedad Espa & ntilde;ola de Otorrinolaringolog & iacute;a y Cirug & iacute;a de Cabeza y Cuello. Published by Elsevier Espa & ntilde;a, S.L.U. All rights reserved.
引用
收藏
页码:169 / 176
页数:8
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