Radiopharmaceuticals: A New Vista for Diagnosis and Treatment of Thyroid Cancer

被引:2
作者
Vernekar, Siddhi [1 ]
Budha, Roja Rani [2 ]
Alavala, Rajasekhar Reddy [1 ]
机构
[1] SVKMs NMIMS, Shobhaben Pratapbhai Patel Sch Pharm & Technol Man, VL Mehta Rd, Mumbai 400056, India
[2] Amity Univ, Amity Inst Pharm, Mumbai 410206, Maharashtra, India
关键词
Thyroid cancer; radiopharmaceuticals; radiotherapy; molecular imaging; oncology; thyrotoxicosis; scintigraphy; radioactive iodine; MANAGEMENT; DOSIMETRY; THERAPY; I-131; PET;
D O I
10.2174/0118744710277275231112081003
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Radiopharmaceuticals are in the diagnosis and treatment of cancerous and non-cancerous diseases, and a hope for optimistic effort in the field of nuclear medicine. They play a crucial role in clinical nuclear medicine by providing a tool to comprehend human disease and create efficient treatments. A detailed analysis is provided regarding the crux of molecular imaging including PET and SPECT overview for the detection of cancers. For a specified understanding of radiation therapy, topics include ranging from the selection of radionuclide to its development and manufacture, and dosage requirements to establishing the importance of I-131 Radiotherapy in thyroid cancer. In this review, we also discussed the current state of the art of nuclear medicine in thyroid cancer, including the role of radioiodine (RAI) therapeutic scans in the diagnosis of differentiated thyroid cancer. In addition, we established a brief outlook into the current status of the research in thyroid cancer and discussed the future directions in this field.
引用
收藏
页码:148 / 162
页数:15
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