Exploring the relationship between manual dexterity and cognition in people with multiple sclerosis: 9-hole peg and multiple cognitive functions

被引：1

作者：

Abraham, Rinu ^{[1
,15
]}

Waldman-Levi, Amiya ^{[1
]}

Barrera, Marissa A. ^{[1
]}

Bogaardt, Hans ^{[2
]}

Golan, Daniel ^{[3
,4
]}

Bergmann, Catherine ^{[5
]}

Sullivan, Cynthia ^{[3
,5
]}

Wilken, Jeffrey ^{[5
]}

Zarif, Myassar ^{[6
]}

Bumstead, Barbara ^{[6
]}

Buhse, MariJean ^{[6
,7
]}

Covey, Thomas J. ^{[8
,9
]}

Doniger, Glen M. ^{[10
]}

Penner, Iris-Katharina ^{[11
]}

Hancock, Laura M. ^{[12
]}

Morrow, Sarah A. ^{[13
]}

Giroux, Erin ^{[14
]}

Gudesblatt, Mark ^{[6
]}

机构：

[1] Yeshiva Univ, Katz Sch Sci & Hlth, 1165 Morris Pk Ave, New York, NY USA

[2] Univ Adelaide, Sch Allied Hlth Sci & Practice, Adelaide, Australia

[3] Clalit Hlth Serv, Multiple Sclerosis & Neuroimmunol Ctr, Nazareth, Israel

[4] Technion Israel Inst Technol, Rappaport Fac Med, Haifa, Israel

[5] Washington Neuropsychol Res Grp, Fairfax, VA USA

[6] NYU Langone South Shore Neurol Associates, Islip, NY USA

[7] SUNY Stony Brook, Dept Nursing, Stony Brook, NY USA

[8] SUNY Buffalo, Jacobs Sch Med & Biomed Sci, Dept Neurol, Div Cognit & Behav Neurosci, Buffalo, NY USA

[9] SUNY Buffalo, Jacobs Sch Med & Biomed Sci, Neurosci Program, Buffalo, NY USA

[10] NeuroTrax Corp, Dept Clin Res, Modiin, Israel

[11] Univ Bern, Bern Univ Hosp, Inselspital, Dept Neurol, Bern, Switzerland

[12] Cleveland Clin, Neurol Inst, Sect Neuropsychol, Cleveland, OH USA

[13] Univ Western Ontario, London Hlth Sci Ctr, London, ON, Canada

[14] Alberta Hlth Serv, Edmonton, AB, Canada

[15] Yeshiva Univ, Katz Sch Sci & Hlth, Occupat Therapy Doctorate Program, OTD, 61 Sunset Ter, New York, NY 06074 USA

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2024年 / 88卷

关键词：

Multiple sclerosis; Manual dexterity; Cognition; SYMPTOMS; FATIGUE; BATTERY;

D O I：

10.1016/j.msard.2024.105696

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Aim and Rationale: Problems with manual dexterity and cognition impact the everyday performance of people with multiple sclerosis (PwMS). Accumulated findings point to the relationship between deficits in manual dexterity and auditory domains of cognition with a lack of evidence on visuospatial and verbal aspects of cognitive functioning. Therefore, this study explores the relationship between manual dexterity and cognition in a cohort of PwMS. Method: This cross-sectional study collected data from 63 PwMS aged 22 to 55 through a convenient sampling method. Participants were diagnosed with relapsing -remitting multiple sclerosis (RRMS). Cognition was measured using a multi -domain computerized cognitive testing, NeuroTrax, and manual dexterity was measured using a 9 -hole peg assessment. Spearman correlation was used to identify the correlation among cognition subtests as well as with manual dexterity. Linear regression analysis was also conducted to identify whether manual dexterity predicts cognitive functioning. Results: A significant negative correlation was found between 9 -hole peg scores and global cognitive scores (GCS), r = -0.34, p = 006. The manual dexterity scores were also shown to predict GCS, R 2 = 0.165, p = 0.001. Conclusion: Manual dexterity was found to not only predict cognitive dysfunction but was also associated with multiple cognitive domains. Understanding the relationship between manual dexterity and cognition and the inferred progression of deficits can assist clinicians to provide interventions at earlier stages of disease progression to potentially increase daily functioning and quality of life (QoL).

引用

页数：5