Transforming our understanding of species-specific gene regulation

被引：0
|
作者：
Dennis, Megan Y. [1 ,2 ]
机构：
[1] Univ Calif Davis, Genome Ctr, Dept Biochem & Mol Med, Davis, CA 95616 USA
[2] Univ Calif Davis, MIND Inst, Davis, CA 95616 USA
来源：
CELL GENOMICS | 2024年 / 4卷 / 04期
基金：
美国国家卫生研究院; 美国国家科学基金会;
关键词：
CIS; EVOLUTION;
D O I：
10.1016/j.xgen.2024.100540
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Mechanisms underlying phenotypic divergence across species remain unresolved. In this issue of Cell Genomics , Hansen, Fong, et al. 1 systematically dissect human and rhesus macaque gene expression divergence by screening tens of thousands of orthologous elements for enhancer activity in lymphoblastoid cell lines, revealing a much greater role for trans divergence at levels equal to those of cis effects, counter to the prevailing consensus in the field.
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Species-specific shells: Chitin synthases and cell mechanics in molluscs
    Weiss, Ingrid M.
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-CRYSTALLINE MATERIALS, 2012, 227 (11): : 723 - 738
  • [32] Bidirectional Promoters as Important Drivers for the Emergence of Species-Specific Transcripts
    Gotea, Valer
    Petrykowska, Hanna M.
    Elnitski, Laura
    PLOS ONE, 2013, 8 (02):
  • [33] Temperature has species-specific effects on corticosterone in alligator lizards
    Telemeco, Rory S.
    Addis, Elizabeth A.
    GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2014, 206 : 184 - 192
  • [34] Active Process Mediates Species-Specific Tuning of Drosophila Ears
    Riabinina, Olena
    Dai, Mingjie
    Duke, Thomas
    Albert, Joerg T.
    CURRENT BIOLOGY, 2011, 21 (08) : 658 - 664
  • [35] Endogenous retroviruses function as species-specific enhancer elements in the placenta
    Chuong, Edward B.
    Rumi, M. A. Karim
    Soares, Michael J.
    Baker, Julie C.
    NATURE GENETICS, 2013, 45 (03) : 325 - 329
  • [36] Species-Specific Dynamic Responses of Gut Bacteria to a Mammalian Glycan
    Raghavan, Varsha
    Groisman, Eduardo A.
    JOURNAL OF BACTERIOLOGY, 2015, 197 (09) : 1538 - 1548
  • [37] Species-specific microsymbiont discrimination mediated by a Medicago receptor kinase
    Yu, Xiaocheng
    Liu, Jinge
    Qin, Qiulin
    Zribi, Ikram
    Yu, Jingyin
    Yang, Shengming
    Dinkins, Randy D.
    Fei, Zhangjun
    Kereszt, Attila
    Zhu, Hongyan
    SCIENCE ADVANCES, 2024, 10 (31):
  • [38] Species-specific differences determine responses to a resource pulse and predation
    Miller, Thomas E.
    Buhler, Maya L.
    Cuellar-Gempeler, Catalina
    OECOLOGIA, 2019, 190 (01) : 169 - 178
  • [39] Systematic analysis of the Capsicum ERF transcription factor family: identification of regulatory factors involved in the regulation of species-specific metabolites
    Song, Jiali
    Chen, Changming
    Zhang, Shuanglin
    Wang, Juntao
    Huang, Zhubing
    Chen, Muxi
    Cao, Bihao
    Zhu, Zhangsheng
    Lei, Jianjun
    BMC GENOMICS, 2020, 21 (01)
  • [40] On the epigenetic evolution of species-specific perception: the developmental manifold concept
    Gottlieb, G
    COGNITIVE DEVELOPMENT, 2002, 17 (3-4) : 1287 - 1300
12345