Assessment of Calcaneal Spongy Bone Magnetic Resonance Characteristics in Women: A Comparison between Measures Obtained at 0.3 T, 1.5 T, and 3.0 T

被引:0
作者
Capuani, Silvia [1 ,2 ]
Maiuro, Alessandra [1 ,3 ]
Giampa, Emiliano [4 ]
Montuori, Marco [1 ]
Varrucciu, Viviana [5 ]
Hagberg, Gisela E. [6 ]
Vinicola, Vincenzo [4 ]
Colonna, Sergio [5 ]
机构
[1] Sapienza Univ Rome, CNR ISC, Phys Dept, Piazzale Aldo Moro 5, I-00185 Rome, Italy
[2] IRCCS Rome, Santa Lucia Fdn, Neuroimaging Lab, Via Ardeatina 309, I-00179 Rome, Italy
[3] Sapienza Univ Rome, Phys Dept, Pzle Aldo Moro 5, I-00185 Rome, Italy
[4] IRCCS Rome, Rehabil Hosp, Santa Lucia Fdn, Via Ardeatina 309, I-00179 Rome, Italy
[5] IRCCS Rome, Santa Lucia Fdn, Radiol Dept, Via Ardeatina 309, I-00179 Rome, Italy
[6] Max Planck Inst Biol Cybernet, High Field Magnet Resonance, D-72076 Tubingen, Germany
关键词
MRI; low magnetic field; high magnetic field; spongy bone; bone marrow fat; SINGLE-SIDED NMR; HIGH-RESOLUTION MRI; TRABECULAR BONE; MARROW FAT; LOW-FIELD; CANCELLOUS BONE; VOLUME FRACTION; HUMAN BRAIN; OSTEOPOROSIS; DIFFUSION;
D O I
10.3390/diagnostics14101050
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: There is a growing interest in bone tissue MRI and an even greater interest in using low-cost MR scanners. However, the characteristics of bone MRI remain to be fully defined, especially at low field strength. This study aimed to characterize the signal-to-noise ratio (SNR), T2, and T2* in spongy bone at 0.3 T, 1.5 T, and 3.0 T. Furthermore, relaxation times were characterized as a function of bone-marrow lipid/water ratio content and trabecular bone density. Methods: Thirty-two women in total underwent an MR-imaging investigation of the calcaneus at 0.3 T, 1.5 T, and 3.0 T. MR-spectroscopy was performed at 3.0 T to assess the fat/water ratio. SNR, T2, and T2* were quantified in distinct calcaneal regions (ST, TC, and CC). ANOVA and Pearson correlation statistics were used. Results: SNR increase depends on the magnetic field strength, acquisition sequence, and calcaneal location. T2* was different at 3.0 T and 1.5 T in ST, TC, and CC. Relaxation times decrease as much as the magnetic field strength increases. The significant linear correlation between relaxation times and fat/water found in healthy young is lost in osteoporotic subjects. Conclusion: The results have implications for the possible use of relaxation vs. lipid/water marrow content for bone quality assessment and the development of quantitative MRI diagnostics at low field strength.
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页数:16
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