Deep Brain Stimulation Mechanisms in Parkinson's Disease: Immediate and Long-Term Effects

被引:2
|
作者
Pei, Honglong [1 ]
Wu, Zhenghan [1 ]
Ma, Li [1 ]
Wang, Jun [1 ]
Li, Jinghui [1 ]
Geng, Xin [1 ]
Zou, Yanghong [1 ]
Zhang, Mou [1 ]
Qi, Renli [1 ]
Yu, Hualin [1 ]
机构
[1] Kunming Med Univ, Affiliated Hosp 1, Dept Neurosurg 2, Kunming 650101, Yunnan, Peoples R China
关键词
basal ganglia; beta oscillations; deep brain stimulation; neuroprotection; neurotransmitters; Parkinson's disease; HIGH-FREQUENCY STIMULATION; SUBTHALAMIC NUCLEUS STIMULATION; STRIATAL DOPAMINE RELEASE; GLOBUS-PALLIDUS INTERNA; BASAL GANGLIA; ALPHA-SYNUCLEIN; ELECTRICAL-STIMULATION; PEDUNCULOPONTINE NUCLEUS; NEUROTROPHIC FACTOR; BETA OSCILLATIONS;
D O I
10.31083/j.jin2306114
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Deep brain stimulation (DBS) is a common therapy for managing Parkinson's disease (PD) in clinical practice. However, a complete understanding of its mode of action is still needed. DBS is believed to work primarily through electrical and neurochemical pathways. Furthermore, DBS has other mechanisms of action. This review explores the fundamental concepts and applications of DBS in treating PD, including its mechanisms, clinical implications, and recent research.
引用
收藏
页数:18
相关论文
共 50 条
  • [31] Deep brain stimulation modulates effects of motivation in Parkinson's disease
    Sauleau, Paul
    Eusebio, Alexandre
    Vandenberghe, Wim
    Nuttin, Bart
    Brown, Peter
    NEUROREPORT, 2009, 20 (06) : 622 - 626
  • [32] Long-term safety and efficacy of frameless subthalamic deep brain stimulation in Parkinson's disease
    Genovese, Danilo
    Bove, Francesco
    Rigon, Leonardo
    Tufo, Tommaso
    Izzo, Alessandro
    Calabresi, Paolo
    Bentivoglio, Anna Rita
    Piano, Carla
    NEUROLOGICAL SCIENCES, 2024, 45 (02) : 565 - 572
  • [33] Long-Term Effects of Pallidal or Subthalamic Deep Brain Stimulation on Quality of Life in Parkinson's Disease
    Volkmann, Jens
    Albanese, Alberto
    Kulisevsky, Jaime
    Tornqvist, Aana-Lena
    Houeto, Jean-Luc
    Pidoux, Bernard
    Bonnet, Anne-Marie
    Mendes, Alexandre
    Benabid, Alim-Louis
    Fraix, Valerie
    Van Blercom, Nadege
    Xie, Jing
    Obeso, Jose
    Cruz Rodriguez-Oroz, Maria
    Guridi, Jurge
    Schnitzler, Alfons
    Timmermann, Lars
    Gironell, Alexandre A.
    Molet, Juan
    Pascual-Sedano, Benta
    Rehncrona, Stig
    Moro, Elena
    Lang, Anthony C.
    Lozano, Andres M.
    Bentivoglio, Anna Rita
    Scerrati, Massimo
    Contarino, Maria Fiorella
    Romito, Luigi
    Janssens, Marc
    Agid, Yves
    MOVEMENT DISORDERS, 2009, 24 (08) : 1154 - 1161
  • [34] Short and Long-Term Cognitive Effects of Subthalamic Deep Brain Stimulation in Parkinson's Disease and Identification of Relevant Factors
    Jahanshahi, Marjan
    Leimbach, Friederike
    Rawji, Vishal
    JOURNAL OF PARKINSONS DISEASE, 2022, 12 (07) : 2191 - 2209
  • [35] Studies of the neural mechanisms of deep brain stimulation in rodent models of Parkinson's disease
    Chang, Jing-Yu
    Shi, Li-Hong
    Luo, Fei
    Zhang, Wang-Ming
    Woodward, Donald J.
    NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2008, 32 (03) : 352 - 366
  • [36] Studies of the neural mechanisms of deep brain stimulation in rodent models of Parkinson's disease
    Chang, Jing-Yu
    Shi, Li-Hong
    Luo, Fel
    Zhang, Wang-Ming
    Woodward, Donald J.
    NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2007, 31 (05) : 643 - 657
  • [37] The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson's disease
    Tinkhauser, Gerd
    Pogosyan, Alek
    Little, Simon
    Beudel, Martijn
    Herz, Damian M.
    Tan, Huiling
    Brown, Peter
    BRAIN, 2017, 140 : 1053 - 1067
  • [38] Apathy and deep brain stimulation in Parkinson's disease
    Lozachmeur, C.
    Drapier, D.
    REVUE NEUROLOGIQUE, 2012, 168 (8-9) : 620 - 623
  • [39] Update on deep brain stimulation in Parkinson's disease
    Martinez-Ramirez, Daniel
    Hu, Wei
    Bona, Alberto R.
    Okun, Michael S.
    Shukla, Aparna Wagle
    TRANSLATIONAL NEURODEGENERATION, 2015, 4
  • [40] Predictive Factors for Long-term Outcome of Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease
    Fukaya, Chikashi
    Watanabe, Mitsuru
    Kobayashi, Kazutaka
    Oshima, Hideki
    Yoshino, Atsuo
    Yamamoto, Takamitsu
    NEUROLOGIA MEDICO-CHIRURGICA, 2017, 57 (04) : 166 - 171