Deep Brain Stimulation Mechanisms in Parkinson's Disease: Immediate and Long-Term Effects

被引：2

作者：

Pei, Honglong ^{[1
]}

Wu, Zhenghan ^{[1
]}

Ma, Li ^{[1
]}

Wang, Jun ^{[1
]}

Li, Jinghui ^{[1
]}

Geng, Xin ^{[1
]}

Zou, Yanghong ^{[1
]}

Zhang, Mou ^{[1
]}

Qi, Renli ^{[1
]}

Yu, Hualin ^{[1
]}

机构：

[1] Kunming Med Univ, Affiliated Hosp 1, Dept Neurosurg 2, Kunming 650101, Yunnan, Peoples R China

来源：

JOURNAL OF INTEGRATIVE NEUROSCIENCE | 2024年 / 23卷 / 06期

关键词：

basal ganglia; beta oscillations; deep brain stimulation; neuroprotection; neurotransmitters; Parkinson's disease; HIGH-FREQUENCY STIMULATION; SUBTHALAMIC NUCLEUS STIMULATION; STRIATAL DOPAMINE RELEASE; GLOBUS-PALLIDUS INTERNA; BASAL GANGLIA; ALPHA-SYNUCLEIN; ELECTRICAL-STIMULATION; PEDUNCULOPONTINE NUCLEUS; NEUROTROPHIC FACTOR; BETA OSCILLATIONS;

D O I：

10.31083/j.jin2306114

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Deep brain stimulation (DBS) is a common therapy for managing Parkinson's disease (PD) in clinical practice. However, a complete understanding of its mode of action is still needed. DBS is believed to work primarily through electrical and neurochemical pathways. Furthermore, DBS has other mechanisms of action. This review explores the fundamental concepts and applications of DBS in treating PD, including its mechanisms, clinical implications, and recent research.

引用

页数：18

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