Vitamin D deficiency and lower respiratory tract infections in children: a systematic review and meta-analysis of observational studies

被引：38

作者：

Jat, Kana Ram ^{[1
]}

机构：

[1] All India Inst Med Sci, Dept Paediat, New Delhi 110029, India

来源：

TROPICAL DOCTOR | 2017年 / 47卷 / 01期

关键词：

Vitamin D; lower respiratory tract infection (LRTI); cohort; case-control study; D SUPPLEMENTATION; SYNCYTIAL VIRUS; NUTRITIONAL RICKETS; RISK; PNEUMONIA; BRONCHIOLITIS; CHILDHOOD; POLYMORPHISMS; ASSOCIATION; FREQUENCY;

D O I：

10.1177/0049475516644141

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Studies related to vitamin D deficiency and lower respiratory tract infections (LRTI) in children have inconsistent findings. The objective of this systematic review was to assess the prevalence of vitamin D deficiency in children with LRTI, and to evaluate the correlation between vitamin D levels and the incidence and severity of LRTI. A total of 12 studies enrolling 2279 participants were included in our analysis. Children with LRTI were found to have significantly lower mean vitamin D levels as compared to controls There was likewise a correlation between vitamin D levels and incidence and severity of LRTI. Large randomised controlled trials are needed to evaluate effect of vitamin D supplementation for LRTI.

引用

页码：77 / 84

页数：8

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