Energy homeostasis in the bone

被引：5

作者：

Zhou, Min ^{[1
,2
,3
,4
]}

An, Yu-Ze ^{[1
,2
,3
,4
]}

Guo, Qi ^{[1
,2
,3
,4
]}

Zhou, Hai-Yan ^{[1
,2
,3
,4
]}

Luo, Xiang-Hang ^{[1
,2
,3
,4
]}

机构：

[1] Cent South Univ, Endocrinol Res Ctr, Dept Endocrinol, Xiangya Hosp, Changsha 410008, Hunan, Peoples R China

[2] Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha 410008, Hunan, Peoples R China

[3] Cent South Univ, Xiangya Hosp, Key Lab Aging Related Bone & Joint Dis Prevent &, Minist Educ, Changsha, Peoples R China

[4] Key Lab Organ Injury Aging & Regenerat Med Hunan, Changsha 410008, Hunan, Peoples R China

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2024年 / 35卷 / 05期

基金：

中国国家自然科学基金;

关键词：

CHAIN FATTY-ACID; INSULIN-RESISTANCE; GLUCOSE-UPTAKE; OSTEOGENIC DIFFERENTIATION; POSTMENOPAUSAL WOMEN; OSTEOCLAST FORMATION; RECEPTOR ACTIVATOR; METABOLISM; OSTEOCALCIN; RANKL;

D O I：

10.1016/j.tem.2023.12.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The bone serves as an energy reservoir and actively engages in whole -body energy metabolism. Numerous studies have determined fuel requirements and bioenergetic properties of bone under physiological conditions as well as the dysregulation of energy metabolism associated with bone metabolic diseases. Here, we review the main sources of energy in bone cells and their regulation, as well as the endocrine role of the bone in systemic energy homeostasis. Moreover, we discuss metabolic changes that occur as a result of osteoporosis. Exploration in this area will contribute to an enhanced comprehension of bone energy metabolism, presenting novel possibilities to address metabolic diseases.

引用

页码：439 / 451

页数：13

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