Energy homeostasis in the bone

被引:5
|
作者
Zhou, Min [1 ,2 ,3 ,4 ]
An, Yu-Ze [1 ,2 ,3 ,4 ]
Guo, Qi [1 ,2 ,3 ,4 ]
Zhou, Hai-Yan [1 ,2 ,3 ,4 ]
Luo, Xiang-Hang [1 ,2 ,3 ,4 ]
机构
[1] Cent South Univ, Endocrinol Res Ctr, Dept Endocrinol, Xiangya Hosp, Changsha 410008, Hunan, Peoples R China
[2] Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha 410008, Hunan, Peoples R China
[3] Cent South Univ, Xiangya Hosp, Key Lab Aging Related Bone & Joint Dis Prevent &, Minist Educ, Changsha, Peoples R China
[4] Key Lab Organ Injury Aging & Regenerat Med Hunan, Changsha 410008, Hunan, Peoples R China
基金
中国国家自然科学基金;
关键词
CHAIN FATTY-ACID; INSULIN-RESISTANCE; GLUCOSE-UPTAKE; OSTEOGENIC DIFFERENTIATION; POSTMENOPAUSAL WOMEN; OSTEOCLAST FORMATION; RECEPTOR ACTIVATOR; METABOLISM; OSTEOCALCIN; RANKL;
D O I
10.1016/j.tem.2023.12.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The bone serves as an energy reservoir and actively engages in whole -body energy metabolism. Numerous studies have determined fuel requirements and bioenergetic properties of bone under physiological conditions as well as the dysregulation of energy metabolism associated with bone metabolic diseases. Here, we review the main sources of energy in bone cells and their regulation, as well as the endocrine role of the bone in systemic energy homeostasis. Moreover, we discuss metabolic changes that occur as a result of osteoporosis. Exploration in this area will contribute to an enhanced comprehension of bone energy metabolism, presenting novel possibilities to address metabolic diseases.
引用
收藏
页码:439 / 451
页数:13
相关论文
共 50 条
  • [21] Bile acid metabolism regulatory network orchestrates bone homeostasis
    Xiang, Tingwen
    Deng, Zihan
    Yang, Chuan
    Tan, Jiulin
    Dou, Ce
    Luo, Fei
    Chen, Yueqi
    PHARMACOLOGICAL RESEARCH, 2023, 196
  • [22] Macrophage Polarization and the Regulation of Bone Immunity in Bone Homeostasis
    Hu, Kangyi
    Shang, Zhengya
    Yang, Xiaorui
    Zhang, Yongjie
    Cao, Linzhong
    JOURNAL OF INFLAMMATION RESEARCH, 2023, 16 : 3563 - 3580
  • [23] Vitamin D and energy homeostasis-of mice and men
    Bouillon, Roger
    Carmeliet, Geert
    Lieben, Liesbet
    Watanabe, Mitsuhiro
    Perino, Alessia
    Auwerx, Johan
    Schoonjans, Kristina
    Verstuyf, Annemieke
    NATURE REVIEWS ENDOCRINOLOGY, 2014, 10 (02) : 79 - 87
  • [24] Involvement of TRPV1 Channels in Energy Homeostasis
    Christie, Stewart
    Wittert, Gary A.
    Li, Hui
    Page, Amanda J.
    FRONTIERS IN ENDOCRINOLOGY, 2018, 9
  • [25] Ghrelin: A Link Between Energy Homeostasis and the Immune System
    Chowen, Julie A.
    Argente, Jesus
    ENDOCRINOLOGY, 2017, 158 (07) : 2077 - 2081
  • [26] Placental Regulation of Energy Homeostasis During Human Pregnancy
    Armistead, Brooke
    Johnson, Eugenia
    VanderKamp, Robert
    Kula-Eversole, Elzbieta
    Kadam, Leena
    Drewlo, Sascha
    Kohan-Ghadr, Hamid-Reza
    ENDOCRINOLOGY, 2020, 161 (07)
  • [27] Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis
    Dai, Bingyang
    Xu, Jiankun
    Li, Xu
    Huang, Le
    Hopkins, Chelsea
    Wang, Honglian
    Yao, Hao
    Mi, Jie
    Zheng, Lizhen
    Wang, Jiali
    Tong, Wenxue
    Chow, Dick Ho-Kiu
    Li, Ye
    He, Xuan
    Hu, Peijie
    Chen, Ziyi
    Zu, Haiyue
    Li, Yixuan
    Yao, Yao
    Jiang, Qing
    Qin, Ling
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [28] Autophagy in bone homeostasis and the onset of osteoporosis
    Yin, Xing
    Zhou, Chenchen
    Li, Jingtao
    Liu, Renkai
    Shi, Bing
    Yuan, Quan
    Zou, Shujuan
    BONE RESEARCH, 2019, 7 (1)
  • [29] MicroRNA control of bone formation and homeostasis
    Lian, Jane B.
    Stein, Gary S.
    van Wijnen, Andre J.
    Stein, Janet L.
    Hassan, Mohammad Q.
    Gaur, Tripti
    Zhang, Ying
    NATURE REVIEWS ENDOCRINOLOGY, 2012, 8 (04) : 212 - 227
  • [30] The expression and function of microRNAs in bone homeostasis
    Pi, Caixia
    Li, Yi-Ping
    Zhou, Xuedong
    Gao, Bo
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2015, 20 : 119 - 138