Unveiling the Rarity: A Case of a Mixed Neuroendocrine-Non-Neuroendocrine Tumor of the Gastroesophageal Junction

被引:0
作者
Alamin, Faris [1 ]
Sage, Hannah [2 ]
Torres, Isabel [2 ]
Parikh, Jignesh [3 ]
Zayat, Vania [2 ,3 ]
机构
[1] Univ Cent Florida, HCA Osceola Hosp, Internal Med, Orlando, FL USA
[2] Univ Cent Florida, Pathol, Coll Med, Orlando, FL 32816 USA
[3] Orlando Vet Affairs Med Ctr, Pathol, Orlando, FL 32803 USA
关键词
esophageal neuroendocrine; mixed neuroendocrine-non-neuroendocrine neoplasm; acute gi bleed; minens; gastroesophageal junction (gej); CARCINOMA;
D O I
10.7759/cureus.63141
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) are a rare group of heterogeneous tumors, consisting of an endocrine and a nonendocrine component, which can develop throughout the gastrointestinal (GI) tract. This case presents a 70-year-old man with a complex medical history who initially presented with an upper GI bleed. After being stabilized, he underwent an esophagogastroduodenoscopy (EGD) that revealed a suspicious gastroesophageal junction (GEJ) mass. Histopathological studies paired with immunohistochemical investigations of the mass confirmed the rare diagnosis of MiNENs. He then underwent an endoscopic submucosal dissection (ESD) with subsequent chemotherapy and adjunct radiotherapy, with no recurrence noted on post-treatment surveillance. This case highlights the need for an EGD, histopathological examination, and immunohistochemical staining for detecting the underlying etiology of an upper GI bleed.
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页数:6
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