Managing cow's milk protein allergy during the 2022 formula shortage: decision-making among pediatric healthcare providers

被引：0

作者：

Oliveros, Lea V. ^{[1
]}

Brown, Jerry M. ^{[2
]}

Fabbrini, Abigail L. ^{[3
]}

Farrar, Andrew A. ^{[3
]}

Lamos, Luke ^{[2
]}

Florio, Jared ^{[2
]}

Beacker, Jesse ^{[2
]}

Baran, Jessica V. ^{[2
]}

Wilsey, Michael J. ^{[4
]}

机构：

[1] Alabama Coll Osteopath Med, Off Med Educ, Dothan, AL USA

[2] Florida Atlantic Univ, Charles E Schmidt Coll Med, Off Med Educ, Boca Raton, FL 33431 USA

[3] Kansas City Univ, Off Med Educ, Coll Osteopath Med, Kansas City, MO USA

[4] Univ S Florida, Morsani Coll Med, Dept Pediat, Tampa, FL USA

来源：

FRONTIERS IN ALLERGY | 2024年 / 5卷

关键词：

amino acid formula; formula shortage; formula recall; infant nutrition; cow's milk protein allergy; ZS Moments; MANAGEMENT;

D O I：

10.3389/falgy.2024.1359103

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Introduction Cow's milk protein allergy (CMPA) affects 2%-7% of infants and is managed with hypoallergenic formulas. The 2022 recalls of infant formulas due to factors including contamination led to specialty formula shortages, highlighting CMPA management challenges. Understanding healthcare providers' (HCPs) decision-making in transitioning to alternative formulas during shortages is crucial. Limited attention has been given to how pediatric physicians make these choices.Methods This study utilized US HCPs' de-identified survey data to assess driving factors when switching extensively hydrolyzed formulas during shortages.Results 104 eligible HCPs participated, including general pediatrics, pediatric allergy/immunology, and pediatric gastroenterology specialists. Safety, tolerability, and efficacy were identified as top factors for switching formulas. Formula 1 was considered well-tolerated, patient-accepted, and safe by all HCPs. Most expressed strong belief in Formula 1's safety and effectiveness.Discussion Findings inform CMPA management during shortages, offering guidance to HCPs for suitable formula selection and enhanced infant care.

引用

页数：8

共 50 条

[31] Extensive protein hydrolysate formula effectively reduces regurgitation in infants with positive and negative challenge tests for cow's milk allergy [J].

Vandenplas, Y. ;

De Greef, E. .

ACTA PAEDIATRICA, 2014, 103 (06) :E243-E250

[32] Cost-effectiveness of using an extensively hydrolyzed casein formula supplemented with Lactobacillus rhamnosus GG in managing IgE-mediated cow's milk protein allergy in the UK [J].

Guest, Julian F. ;

Singh, Heenal .

CURRENT MEDICAL RESEARCH AND OPINION, 2019, 35 (10) :1677-1685

[33] Consensus on the diagnosis and treatment of cow's milk protein allergy of the Latin American Society for Pediatric Gastroenterology, Hepatology and Nutrition [J].

Toca, M. C. ;

Morais, M. B. ;

Vazquez-Frias, R. ;

Becker-Cuevas, D. J. ;

Boggio-Marzet, C. G. ;

Delgado-Carbajal, L. ;

Higuera-Carrillo, M. M. ;

Ladino, L. ;

Marchisone, S. ;

Messere, G. C. ;

Ortiz, G. J. ;

Ortiz-Paranza, L. R. ;

Ortiz-Piedrahita, C. ;

Riveros-Lopez, J. P. ;

Sosa, P. C. ;

Villalobos-Palencia, N. C. .

REVISTA DE GASTROENTEROLOGIA DE MEXICO, 2022, 87 (02) :235-250

[34] Oral Immunotherapy Using Partially Hydrolyzed Formula for Cow's Milk Protein Allergy: A Randomized, Controlled Trial [J].

Inuo, Chisato ;

Tanaka, Kenichi ;

Suzuki, Satoko ;

Nakajima, Yoichi ;

Yamawaki, Kazuo ;

Tsuge, Ikuya ;

Urisu, Atsuo ;

Kondo, Yasuto .

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 2018, 177 (03) :259-268

[35] Overdiagnosis and industry influence: how cow's milk protein allergy is extending the reach of infant formula manufacturers [J].

van Tulleken, Chris .

BMJ-BRITISH MEDICAL JOURNAL, 2018, 363

[36] Relative cost-effectiveness of using an extensively hydrolyzed casein formula in managing infants with cow's milk allergy in Brazil [J].

Guest, Julian F. ;

Yang, Ariana C. ;

Oba, Jane ;

Rodrigues, Maraci ;

Caetano, Rosane ;

Polster, Lilian .

CLINICOECONOMICS AND OUTCOMES RESEARCH, 2016, 8 :629-639

[37] Cost-effectiveness of using an extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG in managing infants with cow's milk allergy in the US [J].

Guest, Julian F. ;

Kobayashi, Roger H. ;

Mehta, Vinay ;

Neidich, Gary .

CURRENT MEDICAL RESEARCH AND OPINION, 2018, 34 (09) :1539-1548

[38] Growth, tolerance and safety outcomes with use of an extensively hydrolyzed casein-based formula in infants with cow's milk protein allergy [J].

Kansu, Aydan ;

Urganci, Nafiye ;

Bukulmez, Aysegul ;

Kutluk, Gunsel ;

Taskin, Didem Gulcu ;

Keskin, Lutfiye Sahin ;

Igde, Mahir ;

Molon, Lutfi ;

Dogan, Yasar ;

Sekerel, Bulent Enis ;

Yuksek, Mutlu ;

Bostanci, Ilknur ;

Gerenli, Nelgin ;

Polat, Esra ;

Dalgic, Buket ;

Ayyildiz, Hasret ;

Usta, Merve ;

Basturk, Ahmet ;

Kirmemis, Ozlem Yuce ;

Kirsaclioglu, Ceyda Tuna ;

Gulerman, Hacer Fulya ;

Sarioglu, Aysugul Alptekin ;

Erdogan, Simge .

FRONTIERS IN PEDIATRICS, 2023, 11

[39] Efficacy of an extensively hydrolyzed formula with the addition of synbiotics in infants with cow's milk protein allergy: a real-world evidence study [J].

Soria, Ramiro ;

Del Compare, Monica ;

Sallaberry, Marisa ;

Martin, Graciela ;

Aprigliano, Gustavo ;

Hermida, Veronica ;

Carosella, Mabel ;

Gruenberg, Martin ;

Monsell, Silvana ;

Micone, Paula ;

Maciero, Eugenia ;

Giglio, Norberto .

FRONTIERS IN ALLERGY, 2023, 4

[40] Reconfirmation of improved tolerance to a new amino acid-based formula by infants with cow's milk protein allergy [J].

Jirapinyo, Pipop ;

Densupsoontorn, Narumon ;

Kangwanpornsiri, Channagan ;

Wongarn, Renu ;

Tirapongporn, Hathaichanok ;

Chotipanang, Kwanjai ;

Phuangphan, Phakkanan .

ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION, 2017, 26 (06) :1088-1091

← 1 2 3 4 5 →