A review of topical micro- and nanoemulsions for common skin diseases

被引：2

作者：

Yousefpoor, Yaser ^{[1
,2
]}

Baharifar, Hadi ^{[3
]}

Esnaashari, Seyedeh Sara ^{[4
]}

Gheybi, Fatemeh ^{[5
,6
]}

Mehrabi, Mohsen ^{[7
]}

Osanloo, Mahmoud ^{[8
]}

Shirshahi, Vahid ^{[7
]}

Amani, Amir ^{[9
]}

机构：

[1] Torbat Heydariyeh Univ Med Sci, Sch Paramed Sci, Dept Med Biotechnol, Torbat Heydariyeh, Iran

[2] Torbat Heydariyeh Univ Med Sci, Res Ctr Adv Technol Med, Torbat Heydariyeh, Iran

[3] Islamic Azad Univ, Sci & Res Branch, Dept Med Nanotechnol, Appl Biophoton Res Ctr, Tehran, Iran

[4] Islamic Azad Univ, Dept Med Nanotechnol, Fac Adv Sci & Technol, Tehran Med Sci, Tehran, Iran

[5] Mashhad Univ Med Sci, Dept Med Biotechnol & Nanotechnol, Fac Med, Mashhad, Iran

[6] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Nanotechnol Res Ctr, Mashhad, Iran

[7] Shahroud Univ Med Sci, Sch Med, Dept Med Nanotechnol, Shahroud, Iran

[8] Fasa Univ Med Sci, Sch Adv Technol Med, Dept Med Nanotechnol, Fasa, Iran

[9] North Khorasan Univ Med Sci, Nat Prod & Med Plants Res Ctr, Bojnurd, Iran

来源：

NANOMEDICINE JOURNAL | 2024年 / 11卷 / 03期

关键词：

Infections; Microemulsion; Nanoemulsion; Skin; Skin care; Skin disease; Topical; DRUG-DELIVERY-SYSTEM; MICROEMULSION-BASED GEL; IN-VITRO EVALUATION; EX-VIVO PERMEATION; NANO-EMULSIONS; PHYSICOCHEMICAL PROPERTIES; TRETINOIN MICROEMULSION; ANTIBACTERIAL ACTIVITY; STAPHYLOCOCCUS-AUREUS; TRANSDERMAL DELIVERY;

D O I：

10.22038/NMJ.2024.75403.1829

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Microemulsions (MEs) and nanoemulsions (NEs) are dispersions of two immiscible liquids which are usually transparent/translucent. Several reports are available on uses of MEs/NEs to increase efficacy of the loaded active ingredient(s) in topical dosage forms. This review aims to describe brief applications of MEs/ NEs in common skin diseases as well as skincare products. Advantages of MEs/NEs in comparison with the traditional bulk form, including their improved efficacy and safety, have been discussed to highlight the importance of use of such delivery systems. The review briefs mechanism of action of MEs/NEs in enhancing delivery of the cargo. Furthermore, applications of MEs/NEs in common skin diseases including infectious rashes, pigmentation disorders (hyperpigmentaion and hypopigmentation), wound healing, skin cancers and scaling patches and plaques/papulosquamous disorders (psoriasis, atopic dermatitis and acne) have been discussed. MEs/NEs in skin care products have also been reviewed here.

引用

页码：205 / 221

页数：17

共 174 条

[41] Impetigo: A need for new therapies in a world of increasing antimicrobial resistance [J].