Vagus Nerve Stimulation Therapy in Epilepsy: An Overview of Technical and Surgical Method, Patient Selection, and Treatment Outcomes

被引：0
|
作者：
Abdennadher, Myriam [1 ]
Rohatgi, Pratik [2 ]
Saxena, Aneeta [3 ]
机构：
[1] Boston Univ, Boston Med Ctr, Neurol Dept, Chobanian & Avedisian Sch Med, Boston, MA 02118 USA
[2] Boston Univ, Boston Med Ctr, Neurosurg Dept, Chobanian & Avedisian Sch Med, Boston, MA 02118 USA
[3] Biogen Idec Inc, Cambridge, MA 02142 USA
来源：
BRAIN SCIENCES | 2024年 / 14卷 / 07期
关键词：
seizure; vagus nerve stimulation; epilepsy; neuromodulation; surgery; epilepsy comorbidity; QUALITY-OF-LIFE; DRUG-RESISTANT EPILEPSY; CORPUS CALLOSOTOMY; PARTIAL SEIZURES; CHRONIC STROKE; FOLLOW-UP; SAFETY; VNS; IMPLANTATION; EFFICACY;
D O I：
10.3390/brainsci14070675
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Epilepsy affects over 65 million people worldwide. One-third of people with epilepsy do not respond to medication and may benefit from surgery. Vagus nerve stimulation (VNS) is the first neuromodulation therapy for the treatment of drug-resistant epilepsy. This method is used in combination with anti-seizure medications in adults and in the pediatric population. VNS has also been demonstrated to have benefits for some epilepsy comorbidities, such as depression, and can be used in combination with other neuromodulation therapies in epilepsy. The authors present an overview of VNS physiology, patient selection, surgery and risks, neuromodulation therapy, and application to epilepsy comorbidities.
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页数：13
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