Vagus Nerve Stimulation Therapy in Epilepsy: An Overview of Technical and Surgical Method, Patient Selection, and Treatment Outcomes

被引：0

作者：

Abdennadher, Myriam ^{[1
]}

Rohatgi, Pratik ^{[2
]}

Saxena, Aneeta ^{[3
]}

机构：

[1] Boston Univ, Boston Med Ctr, Neurol Dept, Chobanian & Avedisian Sch Med, Boston, MA 02118 USA

[2] Boston Univ, Boston Med Ctr, Neurosurg Dept, Chobanian & Avedisian Sch Med, Boston, MA 02118 USA

[3] Biogen Idec Inc, Cambridge, MA 02142 USA

来源：

BRAIN SCIENCES | 2024年 / 14卷 / 07期

关键词：

seizure; vagus nerve stimulation; epilepsy; neuromodulation; surgery; epilepsy comorbidity; QUALITY-OF-LIFE; DRUG-RESISTANT EPILEPSY; CORPUS CALLOSOTOMY; PARTIAL SEIZURES; CHRONIC STROKE; FOLLOW-UP; SAFETY; VNS; IMPLANTATION; EFFICACY;

D O I：

10.3390/brainsci14070675

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Epilepsy affects over 65 million people worldwide. One-third of people with epilepsy do not respond to medication and may benefit from surgery. Vagus nerve stimulation (VNS) is the first neuromodulation therapy for the treatment of drug-resistant epilepsy. This method is used in combination with anti-seizure medications in adults and in the pediatric population. VNS has also been demonstrated to have benefits for some epilepsy comorbidities, such as depression, and can be used in combination with other neuromodulation therapies in epilepsy. The authors present an overview of VNS physiology, patient selection, surgery and risks, neuromodulation therapy, and application to epilepsy comorbidities.

引用

页数：13

共 50 条

[31] Vagus nerve stimulation in patients with therapy-resistant generalized epilepsy
Marti, Ana Suller
Mirsattari, Seyed Mohammad
MacDougall, Keith
Steven, David Andrew
Parrent, Andrew
de Ribaupierre, Sandrine
Andrade, Andrea
Diosy, David
McLachlan, Richard Scott
Burneo, Jorge Guillermo
EPILEPSY & BEHAVIOR, 2020, 111
[32] Vagus nerve stimulation therapy in depression and epilepsy: therapeutic parameter settings
Labiner, David M.
Ahern, Geoffrey L.
ACTA NEUROLOGICA SCANDINAVICA, 2007, 115 (01): : 23 - 33
[33] Vagus nerve stimulation lead removal or replacement: surgical technique, institutional experience, and literature overview
Aalbers, Marlien W.
Rijkers, Kim
Klinkenberg, Sylvia
Majoie, Marian
Cornips, Erwin M. J.
ACTA NEUROCHIRURGICA, 2015, 157 (11) : 1917 - 1924
[34] Can we predict the response in the treatment of epilepsy with vagus nerve stimulation?
Arcos, A.
Romero, L.
Gelabert, M.
Prieto, A.
Pardo, J.
Rodriguez Osorio, X.
Arraez, M. A.
NEUROSURGICAL REVIEW, 2014, 37 (04) : 661 - 667
[35] Vocal cord adduction during vagus nerve stimulation for treatment of epilepsy
Zumsteg, D
Jenny, D
Wieser, HG
NEUROLOGY, 2000, 54 (06) : 1388 - 1389
[36] Vagus nerve stimulation for children with treatment-resistant epilepsy: a consecutive series of 141 cases Clinical article
Elliott, Robert E.
Rodgers, Shaun D.
Bassani, Luigi
Morsi, Amr
Geller, Eric B.
Carlson, Chad
Devinsky, Orrin
Doyle, Werner K.
JOURNAL OF NEUROSURGERY-PEDIATRICS, 2011, 7 (05) : 491 - 500
[37] The place of vagus nerve stimulation in the treatment of epilepsy
Schmidt, D
Elger, CE
Stefan, H
Bergmann, A
Bauer, G
Brandl, U
Despland, P
Dorn, T
Ernst, JP
Flierl, A
Holthausen, H
Luef, G
Körner, E
Krämer, G
Meencke, HJ
Mamoli, B
Merschhemke, M
Noachtar, S
Ott, E
Pohlmann-Eden, B
Runge, U
Scherrmann, J
Schnizer, M
Tettenborn, B
Wieser, HG
NERVENHEILKUNDE, 1999, 18 (10) : 558 - 561
[38] Vagus nerve stimulation for the treatment of refractory epilepsy
Roux, F. -X.
Turak, B.
Landre, E.
NEUROCHIRURGIE, 2008, 54 (03) : 332 - 339
[39] Beneficial effects on sleep of vagus nerve stimulation in children with therapy resistant epilepsy
Hallböök, T
Lundgren, J
Köhler, S
Blennow, G
Strömblad, LG
Rosén, I
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2005, 9 (06) : 399 - 407
[40] Vagus nerve stimulation for epilepsy treatment in children
Hoppe, Christian
Helmstaedter, Christoph
Elger, Christian E.
EPILEPSIA, 2015, 56 (02) : 323 - 324

← 1 2 3 4 5 →