New Strategies for Locally Advanced Breast Cancer: A Review of Inflammatory Breast Cancer and Nonresponders

被引:1
作者
Malhotra, Simran [1 ]
Tadros, Audree B. [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Surger, Breast Serv, 300 East 66th St, New York, NY 10065 USA
关键词
Breast cancer-related lymphedema; Breast surgery; Lymphatic reconstruction; Neoadjuvant systemic therapy; Radiotherapy; LYMPH-NODE TRANSFER; NEOADJUVANT CHEMOTHERAPY; SACITUZUMAB GOVITECAN; BIOPSY; RECONSTRUCTION; EFFICACY; THERAPY; BURDEN; RISK; MRI;
D O I
10.1016/j.clbc.2024.01.009
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This review explores the new strategies around the management of locally advanced breast cancer (LABC), particularly for nonresponsive tumors and/or initially unresectable tumors at diagnosis, inclusive of inflammatory breast cancer. Nonresponders to neoadjuvant systemic therapy present a unique clinical challenge. Emerging medical therapeutics as well as considerations for use of radiotherapy and/or surgery in this setting are discussed. Specifically, the use of neoadjuvant radiotherapy for LABC and lymphedema prevention with lymphatic reconstruction following axillary lymph node dissection are reviewed.
引用
收藏
页码:301 / 309
页数:9
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