An Update on Viral Hepatitis B and C in Mexico: Advances and Pitfalls in Eradication Strategies

被引:0
作者
Campos-Valdez, Marina [1 ]
Castro-Garcia, Manuel Alejandro [1 ]
Ramos-Marquez, Martha Eloisa [1 ]
Gurrola-Diaz, Carmen Magdalena [1 ]
Salazar-Montes, Adriana Maria [1 ]
Sanchez-Orozco, Laura Veronica [1 ]
机构
[1] Univ Guadalajara, Ctr Univ Ciencias Salud, Inst Invest Enfermedades Cron Degenerat, Sierra Mojada 950,Puerta 7,Edificio Q Segundo Nive, Guadalajara 44340, Jalisco, Mexico
关键词
viral hepatitis; hepatitis B; hepatitis C; Mexico; epidemiology; prevention; eradication; INJECTION-DRUG USERS; VIRUS-INFECTION; BLOOD-DONORS; RISK-FACTORS; SEROLOGICAL MARKERS; NATURAL-HISTORY; PREVALENCE; SEROPREVALENCE; ANTIBODIES; GENOTYPE;
D O I
10.3390/microorganisms12071368
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In Mexico, hepatitis B and C infections are a significant burden on the health system. The aim of this narrative review was to analyze the state of the art on hepatitis B and C in Mexico by searching and studying available data in academic articles and government reports and statements on epidemiology, prevention, treatment, and elimination strategies undertaken by the Mexican government. Even where the government has implemented a hepatitis B vaccination strategy to reduce its incidence, a very low proportion of people complete the vaccination schedule. Regarding hepatitis C, there is a National Elimination Program that emphasizes the importance of screening, diagnosis, and treatment focused on the population at risk. With the implementation of this program, more than a million fast tests have been carried out and the positive cases have been verified by viral load. Infected patients are tested to determine liver function, fibrosis stage, and coinfection with HBV and/or HIV. Patients without cirrhosis and/or coinfections are treated in first-level care centers, while those with cirrhosis and/or comorbidities are referred to specialists. The possibility of hepatitis C eradication in Mexico seems more likely than eradication of hepatitis B; however, major challenges remain to be overcome to reach both infections' elimination.
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页数:18
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