Electrochemical Oxidative (4+2) Cyclization of Anilines and o-Phenylenediamines for the Synthesis of Phenazines

被引：1
|
作者：
Huang, Peng-Fei [1 ]
Fu, Jia-Le [1 ]
Peng, Ying [1 ]
Tang, Ke-Wen [1 ]
Liu, Yu [1 ]
机构：
[1] Hunan Inst Sci & Technol, Dept Chem & Chem Engn, Yueyang 414006, Peoples R China
来源：
ORGANIC LETTERS | 2024年 / 26卷 / 18期
基金：
中国国家自然科学基金;
关键词：
N-H IMINES; DIELS-ALDER; ANNULATION; CYCLOADDITION; ACID; BIOSYNTHESIS; ALKENES; ALKYNES;
D O I：
10.1021/acs.orglett.4c00851
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Phenazines, crucial constituents of nitrogen-containing heterocycles, widely exist in functional compounds. Herein, we report an anodic oxidative (4 + 2) cyclization between anilines and o-phenylenediamines for the uniform construction of phenazines in a simple undivided cell. Dual C-H amination followed by oxidation represents an outstanding step and atom efficiency. A sequence of phenazines is produced with excellent functional group tolerance at room temperature.
引用
收藏
页码：3756 / 3761
页数：6
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