The protective effects of some herbs on mitigating HFD-induced obesity via enhancing biochemical indicators and fertility in female rats

被引:5
作者
Abdoon, Ahmed Sabry S. [1 ]
Hegazy, Amany M. [2 ]
Abdel-Azeem, Amal S. [2 ]
Al-Atrash, Ahmed M. [3 ]
Mohammed, Dina Mostafa [2 ,4 ]
机构
[1] Natl Res Ctr, Vet Res Div, Anim Reprod, Dokki, Giza, Egypt
[2] Natl Res Ctr, Nutr & Food Sci Dept, Dokki, Giza, Egypt
[3] Nucl Mat Author, Cairo, Egypt
[4] Natl Res Ctr, Nutr & Food Sci Dept, Dokki, Egypt
关键词
Obesity; Fertility; Chia seeds; Hibiscus sabdariffa L; Foeniculum vulgare (fennel); Coriandrum sativum L. (coriander); HIGH-FAT DIET; INSULIN-RESISTANCE; LIPID-METABOLISM; GENE-EXPRESSION; L; IMPROVES; DYSFUNCTION; STEATOSIS; ENZYME; GROWTH;
D O I
10.1016/j.heliyon.2024.e30249
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The potential of plant -based diets and drugs to prevent and control obesity has been attributed to the presence of several biologically active phytochemicals. The study aimed to assess herb consumption 's impact on alleviating the risks and hazards associated with obesity induced by a highfat diet (HFD) and the promotion of fertility. Eighty rats were allocated into four distinct groups. Group 1 (G1) was provided with a basal diet and acted as the control group. Group 2 (G2) was provided with an HFD. Group 3 (G3) was provided with HFD supplemented with chia seeds and Hibiscus sabdariffa L. The fourth group of subjects was provided with HFD supplemented with Foeniculum vulgare (fennel) and Coriandrum sativum L. (coriander). The feeding session was sustained for 10 weeks, and the biochemical parameters were evaluated. The administration of Foeniculum vulgare (fennel) and Coriandrum sativum L. (coriander) (G4) resulted in a more significant reduction in all biochemical parameters compared to G3, which received a diet consisting of chia seeds and Hibiscus sabdariffa L. Additionally, the average number of embryonic lobes and the average number of offspring after birth were found to be considerably more significant in the normal control group (G1) and group (G4) compared to the HFD group (G2) and group (G3) (P < 0.01). Group 4 (G4) was administered a diet enriched with Foeniculum vulgare (fennel) and Coriandrum sativum L. (coriander), which demonstrated superior outcomes in many biochemical indicators and the promotion of fertility in obese female rats.
引用
收藏
页数:12
相关论文
共 86 条
[1]  
Elghazaly NAA, 2019, Journal Of Obesity Management, V1, P16, DOI 10.14302/issn.2574-450x.jom-18-2484
[2]   Cellular lipid metabolism and the role of lipids in progressive renal disease [J].
Abrass, CK .
AMERICAN JOURNAL OF NEPHROLOGY, 2004, 24 (01) :46-53
[3]  
AEBI H, 1984, METHOD ENZYMOL, V105, P121
[4]   Hypoglycemic and hypolipidemic effects of Coriandrum sativum L. in Meriones shawi rats [J].
Aissaoui, Abderrahmane ;
Zizi, Soumia ;
Israili, Zafar H. ;
Lyoussi, Badiaa .
JOURNAL OF ETHNOPHARMACOLOGY, 2011, 137 (01) :652-661
[5]   Effect of Hibiscus sabdariffia on obesity in MSG mice [J].
Alarcon-Aguilar, Francisco J. ;
Zamilpa, Alejandro ;
Perez-Garcia, Ma. Dolores ;
Almanza-Perez, Julio C. ;
Romero-Nunez, Eunice ;
Campos-Sepulveda, Efrain A. ;
Vazquez-Carrillo, Laura I. ;
Roman-Ramos, Ruben .
JOURNAL OF ETHNOPHARMACOLOGY, 2007, 114 (01) :66-71
[6]  
ALLAIN CC, 1974, CLIN CHEM, V20, P470
[7]   Red Beet Peel-Loaded Liposome's Impact on Metabolic Syndrome Rats and Its Use as Fortifier in Yoghurt Powder [J].
Alshafei, Moetazza M. ;
Mohammed, Dina Mostafa ;
Hanafi, Emtenan M. ;
Kassem, Seham S. ;
El-Messery, Tamer M. ;
Korany, Reda M. S. ;
El-Said, Marwa M. .
EGYPTIAN JOURNAL OF CHEMISTRY, 2023, 66 (02) :517-533
[8]   Prophylactic supplementation of microencapsulated Boswellia serrata and probiotic bacteria in metabolic syndrome rats [J].
Alshafei, Moetazza M. ;
Mabrouk, Ahmed M. ;
Hanafi, Emtenan M. ;
Ramadan, Manal M. ;
Korany, Reda M. S. ;
Kassem, Seham S. ;
Mohammed, Dina Mostafa .
FOOD BIOSCIENCE, 2023, 51
[9]   Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats [J].
Amin, Kamal A. ;
Nagy, Mohamed A. .
DIABETOLOGY & METABOLIC SYNDROME, 2009, 1
[10]  
Assal H.S., 2007, J. Med. Sci., V7, P865