The first complete genome of the extinct European wild ass (Equus hemionus hydruntinus)

被引：0

作者：

Ozkan, Mustafa ^{[1
]}

Gurun, Kanat ^{[1
]}

Yuncu, Eren ^{[1
]}

Vural, Kivilcim Basak ^{[1
]}

Atag, Gozde ^{[1
]}

Akbaba, Ali ^{[2
,3
]}

Fidan, Fatma Rabia ^{[1
,4
]}

Saglican, Ekin ^{[5
]}

Altinisik, Ezgi N. ^{[6
]}

Koptekin, Dilek ^{[5
]}

Pawlowska, Kamilla ^{[7
]}

Hodder, Ian ^{[8
]}

Adcock, Sarah E. ^{[9
]}

Arbuckle, Benjamin S. ^{[10
]}

Steadman, Sharon R. ^{[11
]}

McMahon, Gregory ^{[12
]}

Erdal, Yilmaz Selim ^{[6
]}

Bilgin, C. Can ^{[1
]}

Togan, Inci ^{[1
]}

Geigl, Eva-Maria ^{[13
]}

Gotherstrom, Anders ^{[14
]}

Grange, Thierry ^{[13
]}

Ozer, Fuesun ^{[5
]}

Somel, Mehmet ^{[1
]}

机构：

[1] Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye

[2] Ankara Univ, Dept Anthropol, Ankara, Turkiye

[3] Alparslan Univ, Mus, Turkiye

[4] Francis Crick Inst, Canc Dynam Lab, London, England

[5] Middle East Tech Univ, Dept Hlth Informat, Ankara, Turkiye

[6] Hacettepe Univ, Dept Anthropol, Human G Lab, Ankara, Turkiye

[7] Adam Mickiewicz Univ, Dept Palaeoenvironmental Res, Poznan, Poland

[8] Stanford Univ, Dept Anthropol, Stanford, CA USA

[9] NYU, Inst Study Ancient World, New York, NY USA

[10] Univ North Carolina Chapel Hill, Dept Anthropol, Chapel Hill, NC USA

[11] SUNY Coll Cortland, Dept Sociol Anthropol, Cortland, NY USA

[12] Univ New Hampshire, Class Humanities & Italian Studies Dept, Durham, NH USA

[13] Univ Paris, Inst Jacques Monod, CNRS, Paris, France

[14] Stockholm Univ, Dept Archaeol & Class Studies, Stockholm, Sweden

来源：

MOLECULAR ECOLOGY | 2024年 / 33卷 / 14期

基金：

欧洲研究理事会;

关键词：

ancient DNA; Asiatic wild ass; demography; Equus hemionus hydruntinus; population genetics; taxonomy; MULLERIAN MIMICRY; POISON FROGS; PHYLOGENETIC ANALYSIS; MIMETIC RADIATION; EVOLUTION; SEQUENCE; PLEISTOCENE; COLORATION; ACCURATE; EQUIDS;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We present palaeogenomes of three morphologically unidentified Anatolian equids dating to the first millennium BCE, sequenced to a coverage of 0.6-6.4x. Mitochondrial DNA haplotypes of the Anatolian individuals clustered with those of Equus hydruntinus (or Equus hemionus hydruntinus), the extinct European wild ass, secular name 'hydruntine'. Further, the Anatolian wild ass whole genome profiles fell outside the genomic diversity of other extant and past Asiatic wild ass (E. hemionus) lineages. These observations suggest that the three Anatolian wild asses represent hydruntines, making them the latest recorded survivors of this lineage, about a millennium later than the latest observations in the zooarchaeological record. Our mitogenomic and genomic analyses indicate that E. h. hydruntinus was a clade belonging to ancient and present-day E. hemionus lineages that radiated possibly between 0.6 and 0.8 Mya. We also find evidence consistent with recent gene flow between hydruntines and Middle Eastern wild asses. Analyses of genome-wide heterozygosity and runs of homozygosity suggest that the Anatolian wild ass population may have lost genetic diversity by the mid-first millennium BCE, a possible sign of its eventual demise.

引用

页数：19