Evaluation of treatment and long-term management of anaphylaxis in pediatric departments of Greece: a 2-year nationwide survey

被引:0
作者
Chiampou, Evanthia [1 ]
Douros, Konstantinos [2 ]
Moriki, Dafni [2 ]
Marina, Mitrogiorgou [2 ]
Anastasiou-Katsiardani, Anastasia [3 ]
Tanou, Kalliopi [3 ]
Grammeniatis, Vasilis [4 ]
Zisi, Anna [4 ]
Perikleous, Evanthia [4 ]
Galanakis, Emmanouil [5 ]
Lioudaki, Marilia [5 ]
Vrouvaki, Fotini [5 ]
Kolyva, Soultana [6 ]
Mavroudi, Antigoni [7 ]
Nivatsi, Maria [8 ]
Ntouma, Stergianna [9 ]
Stefanaki, Evangelia [10 ]
Triga, Maria [11 ]
Kakava, Panagiota [11 ]
Lagiou, Olga [11 ]
Priftis, Kostas N. [2 ]
Chaliasos, Nikolaos [12 ]
Tsabouri, Sophia [12 ]
机构
[1] Univ Hosp Ioannina, Dept Pediat, Ioannina, Greece
[2] Natl & Kapodistrian Univ Athens, Attikon Univ Hosp, Sch Med, Dept Pediat 3,Pediat Allergy & Resp Unit, Athens, Greece
[3] Achillopouleio Gen Hosp Volos, Dept Paediat, Volos, Thessaly, Greece
[4] Gen Hosp Ioannina, Dept Paediat, Ioannina, Greece
[5] Univ Crete, Univ Hosp, Dept Paediat, Iraklion, Crete, Greece
[6] Gen Hosp Chania, Dept Paediat, Iraklion, Greece
[7] Aristotle Univ Thessaloniki, Hippokrat Hosp, Pediat Dept 3, Thessaloniki, Greece
[8] Aristotle Univ Thessaloniki, Hippokrat Hosp, Pediat Dept, Thessaloniki, Greece
[9] Aristotle Univ Thessaloniki, AHEPA Univ Gen Hosp Thessaloniki, Dept Pediat 2, Thessaloniki, Greece
[10] Venizele Gen Hosp, Dept Pediat, Iraklion, Greece
[11] Univ Hosp Patras, Dept Pediat, Pediat Allergy Unit, Patras, Greece
[12] Univ Ioannina, Child Hlth Dept, Sch Med, Ioannina, Greece
关键词
acute treatment; anaphylaxis; children; epinephrine; long-term management; FOOD-INDUCED ANAPHYLAXIS; EMERGENCY-DEPARTMENT; FATAL ANAPHYLAXIS; EPINEPHRINE ABSORPTION; UNITED-STATES; FOLLOW-UP; CHILDREN; CARE; ALLERGY; RISK;
D O I
暂无
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background: Anaphylaxis proportions of incidence are increasing globally. However, limited data are available regarding anaphylaxis in the pediatric population of Greece. Purpose: The aim of the study was to evaluate management of anaphylaxis in Greek pediatric departments. Methods: We performed a questionnaire-based study of children aged less than 16 years presenting with anaphylaxis in 10 national pediatric hospitals over a period of 2 years. Management of anaphylaxis was assessed prior to and after an informative intervention. Results: In all, 127 cases of anaphylaxis were identified. Epinephrine was administered almost half of all cases (51.2%), predominantly through intramuscular route (88.5%), while majority of anaphylaxis patients were treated with antihistamines (92.9%) and corticosteroids (70.1%). Epinephrine was more likely administered by physicians if the elicitor was a (P < 0.003). Regarding long-term management, an epinephrine auto-injector was prescribed in 66.9% of patients. Follow-up information was available for most of the patients (92.9%), the majority of whom (76.3%) were referred to an allergist. More than half of these patients (63.6%) had a documented allergy follow-up, which identified a causative allergen in 53.3% cases. No statistically significant differences were recorded prior to and after the intervention regarding management of anaphylaxis. Conclusions: This nationwide study highlighted the necessity of further improvement in terms of anaphylaxis treatment and secondary prevention measures. This presupposes appropriate education and training of healthcare professionals, thus contributing to proper and comprehensive care of the pediatric population. (c) 2024 Codon Publications. Published by Codon Publications.
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页码:8 / 16
页数:9
相关论文
共 65 条
[1]   The effect of the COVID-19 pandemic on the provision of outpatient clinic services in East Jerusalem hospitals: patients' perspectives [J].
Ahmead, Muna ;
Daghlas, Firas .
FRONTIERS IN PUBLIC HEALTH, 2023, 11
[2]   Do Corticosteroids Prevent Biphasic Anaphylaxis? [J].
Alqurashi, Waleed ;
Ellis, Anne K. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2017, 5 (05) :1194-1206
[3]   Epidemiology and clinical predictors of biphasic reactions in children with anaphylaxis [J].
Alqurashi, Waleed ;
Stiell, Ian ;
Chan, Kevin ;
Neto, Gina ;
Alsadoon, Abdulaziz ;
Wells, George .
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2015, 115 (03) :217-+
[4]   Anaphylaxis in the Pediatric Emergency Department: Analysis of 133 Cases After an Allergy Workup [J].
Alvarez-Perea, Alberto ;
Ameiro, Beatriz ;
Morales, Cristina ;
Zambrano, Gabriela ;
Rodriguez, Ana ;
Guzman, Miguel ;
Manuel Zubeldia, Jose ;
Baeza, Maria L. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2017, 5 (05) :1256-1263
[5]   Myths, facts and controversies in the diagnosis and management of anaphylaxis [J].
Anagnostou, Katherine ;
Turner, Paul J. .
ARCHIVES OF DISEASE IN CHILDHOOD, 2019, 104 (01) :83-90
[6]   Improving anaphylaxis management in a pediatric emergency department [J].
Arroabarren, E. ;
Lasa, E. M. ;
Olaciregui, I. ;
Sarasqueta, C. ;
Munoz, J. A. ;
Perez-Yarza, E. G. .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2011, 22 (07) :708-714
[7]   COVID-19 and resilience of healthcare systems in ten countries [J].
Arsenault, Catherine ;
Gage, Anna ;
Kim, Min Kyung ;
Kapoor, Neena R. ;
Akweongo, Patricia ;
Amponsah, Freddie ;
Aryal, Amit ;
Asai, Daisuke ;
Awoonor-Williams, John Koku ;
Ayele, Wondimu ;
Bedregal, Paula ;
Doubova, Svetlana, V ;
Dulal, Mahesh ;
Gadeka, Dominic Dormenyo ;
Gordon-Strachan, Georgiana ;
Mariam, Damen Haile ;
Hensman, Dilipkumar ;
Joseph, Jean Paul ;
Kaewkamjornchai, Phanuwich ;
Eshetu, Munir Kassa ;
Gelaw, Solomon Kassahun ;
Kubota, Shogo ;
Leerapan, Borwornsom ;
Margozzini, Paula ;
Mebratie, Anagaw Derseh ;
Mehata, Suresh ;
Moshabela, Mosa ;
Mthethwa, Londiwe ;
Nega, Adiam ;
Oh, Juhwan ;
Park, Sookyung ;
Passi-Solar, Alvaro ;
Perez-Cuevas, Ricardo ;
Phengsavanh, Alongkhone ;
Reddy, Tarylee ;
Rittiphairoj, Thanitsara ;
Sapag, Jaime C. ;
Thermidor, Roody ;
Tlou, Boikhutso ;
Guinez, Francisco Valenzuela ;
Bauhoff, Sebastian ;
Kruk, Margaret E. .
NATURE MEDICINE, 2022, 28 (06) :1314-+
[8]  
Australasian Society of Clinical Immunology and Allergy (ASCIA), Guidelines-Acute Management of Anaphylaxis
[9]   Things We Do for No Reason™: Routine use of corticosteroids for the treatment of anaphylaxis [J].
Auth, Roger Douglas ;
Zheng, Tao ;
Berk, Justin .
JOURNAL OF HOSPITAL MEDICINE, 2022, 17 (03) :211-214
[10]   Review article: Quality of follow-up care for anaphylaxis in the emergency department [J].
Burnell, Fiona J. ;
Keijzers, Gerben ;
Smith, Pete .
EMERGENCY MEDICINE AUSTRALASIA, 2015, 27 (05) :387-393