DDX21 is a new player in co-transcriptional RNA modification and functions

<正>Ever since the first discovery of chemical modifications of RNA in 1951,researchers have been captivated by the diverse types of modifications,their associated enzymes and proteins（writers,erasers,or readers）,and their downstream functional implications（Song and Yi,2017）.Among the over 170 distinct types of RNA modifications identified thus far,N6-methyladenosine（m6A） stands out as the most prevalent internal modification on mammalian messenger RNA（mRNA）(Song and Yi,2017).