Ang-(1-7)及其Mas受体的研究进展

被引:5
|
作者
杜慧
缪朝玉
机构
[1] 第二军医大学药学院药理学教研室
关键词
血管紧张素类; Mas受体; 组织; 疾病;
D O I
暂无
中图分类号
R33 [人体生理学];
学科分类号
摘要
血管紧张素(angiotensin,Ang)-(1-7)是肾素-血管紧张素系统中除AngⅡ以外,另一种重要的调节肽,主要作用于Mas受体发挥作用。Ang-(1-7)通过与其Mas受体的结合,发挥血管扩张和抗细胞增殖等作用,抗衡AngⅡ与其AT1受体结合产生的血管收缩、血压升高、细胞增殖、尿钠潴留等作用。近年来研究发现,Ang-(1-7)及其Mas受体在局部组织生理功能中具有积极作用,在多种疾病病理过程中具有保护作用。
引用
收藏
页码:667 / 671
页数:5
相关论文
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