Biosynthesis and antimicrobial activities of Tinospora cordifolia zinc nanoparticles

被引：7

作者：

Libin K.V. ^{[1
]}

Sisodiya S. ^{[2
]}

Debnath M. ^{[2
]}

机构：

[1] Banasthali Vidyapith, Department of Biosciences and Biotechnology, Rajasthan

[2] Manipal University Jaipur, Department of Biosciences, Rajasthan, Jaipur

来源：

Materials Today: Proceedings | 2023年 / 79卷

关键词：

Antimicrobial; Columbin; Green chemistry; Nanoparticle; Stem extract; Tinospora cordifolia;

D O I：

10.1016/j.matpr.2022.12.159

中图分类号：

学科分类号：

摘要：

Nanoparticles are important features that reflect the size, morphology, and other properties. The current study focuses on the biosynthesis of zinc nanomaterials utilizing Tinospora cordifolia stem extract. Green synthesis of zinc nanoparticles (ZnNPs) can terminate chemical pathogens that may have adverse consequences, hence manufacturing nanoparticles is more accordant with an environmentally sustainable strategy. To better comprehend the therapeutic utility of T. cordifolia (Giloy) in healthcare for the creation of antimicrobial agents, we attempted to combine its medicinal characteristics, possibly with nanotechnology. T.cordifolia has shreds of evidence in traditional Ayurveda for fever, jaundice, chronic diarrhoea, asthma, and various skin diseases. The prepared zinc nanoparticles of the stem extract of. T cordifolia (TSE-ZnO-NP) have been identified by UV–visible spectroscopy, FTIR, EDAX, and FESEM. A surface plasma resonance (SPR) of the prepared nanoparticle was observed at 274 nm. The spherical morphological appearance as seen with FESEM analysis showed a size range of 43.7 nm −87.7 nm and the corresponding zinc content was found to be 59.8 % as per the EDAX analysis. Using the FTIR approach, it was confirmed that the peaks of the standard Columbin showed similarity with the FTIR spectra of the stem extract of T. cordifolia (TSE). It was interesting to note that some of the peaks shown by TSE-ZnO-NP were not visible in the TSE. The sample TSE-ZnO-NP was more effective as an antibacterial agent in comparison to the TSE. The bactericidal action of ZnO-NP is beneficial as a model in the prediction of bacterial resistance against pathogens. This biological synthesis of zinc nanoparticles of Tinospora cordifolia proved to be clean, non-toxic, bactericidal, and environmentally acceptable. © 2022

引用

页码：367 / 374

页数：7

共 19 条

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