Amphiregulin in lung diseases: A review

被引:1
作者
Shen, Chao [1 ]
Fan, Xiaoping [1 ]
Mao, Yueyan [1 ]
Jiang, Junsheng [1 ]
机构
[1] Zhejiang Univ, Affiliated Hosp 2, Dept Pediat, Linping Branch, Hangzhou, Peoples R China
关键词
amphiregulin; lung; respiratory system; EPIDERMAL-GROWTH-FACTOR; GENE-EXPRESSION; FACTOR RECEPTOR; CANCER; CELLS; INHIBITION; RESISTANCE; GEFITINIB; APOPTOSIS;
D O I
10.1097/MD.0000000000037292
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Amphiregulin is a member of the EGFR family, which is involved in many physiological and pathological processes through its binding with EGFR. Studies have found that amphiregulin plays an important role in the occurrence and development of lung diseases. This paper mainly reviews the structure and function of amphiregulin and focuses on the important role of amphiregulin in lung diseases.
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页数:4
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