Impact of SARS-CoV-2 infection on pain crisis and acute chest syndrome in patients with sickle cell anemia: A retrospective multi-cohort study based on US national data from 2020 to 2022

被引：0

作者：

Alvarado, Juan ^{[1
,2
]}

Yerigeri, Keval ^{[1
,2
]}

Boakye, Anita ^{[1
,2
]}

Randolph, Christina ^{[1
,2
]}

Roy, Aparna ^{[1
,2
]}

Onimoe, Grace ^{[1
,2
,3
]}

机构：

[1] Metrohlth Med Syst, Cleveland, OH USA

[2] Case Western Univ, Cleveland, OH USA

[3] 2500 MetroHlth Dr, Cleveland, OH 44109 USA

来源：

EJHAEM | 2024年 / 5卷 / 02期

关键词：

acute chest syndrome; COVID-19; pain; SARS-Cov-2; sickle cell anaemia; sickle cell disease; COVID-19; DISEASE; CHILDREN;

D O I：

10.1002/jha2.840

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

COVID-19 infection has been a significant contributor to global morbidity and mortality, especially among those patients with chronic diseases. The Centers for Disease Control and Prevention have classified sickle cell disease (SCD) as a condition that increases the risk of severe illness from COVID-19 infection.A retrospective study was conducted using the TRiNetX health research network database to identify SCA patients ( HbSS, Sbeta-thalassemia zero) who had SARS-CoV-2 infection over 2 years; these were compared with similar patients who did not have the infection in terms of demographics, pain control, and laboratory parametersCOVID-19 illness impacts [ain crises and ACS, and prior vaccination against influenza and COVID-19 may represent a protective factor for developing pain crises. image

引用

页码：299 / 307

页数：9

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