Tuning chitosan's chemical structure for enhanced biological functions

被引：40

作者：

Aghbashlo, Mortaza ^{[1
,2
]}

Amiri, Hamid ^{[3
,4
]}

Basri, Seyed Masoud Moosavi ^{[5
]}

Rastegari, Hajar ^{[6
]}

Lam, Su Shiung ^{[6
]}

Pan, Junting ^{[1
]}

Gupta, Vijai Kumar ^{[7
,8
]}

Tabatabaei, Meisam ^{[6
]}

机构：

[1] Chinese Acad Agr Sci, Inst Agr Resources & Reg Planning, Beijing 100081, Peoples R China

[2] Univ Tehran, Fac Agr Engn & Technol, Dept Mech Engn Agr Machinery, Coll Agr & Nat Resources, Karaj, Iran

[3] Univ Isfahan, Fac Biol Sci & Technol, Dept Biotechnol, Esfahan 8174673441, Iran

[4] Univ Isfahan, Environm Res Inst, Esfahan 8174673441, Iran

[5] Kuwait Canc Control Ctr KCCC, Kuwait, Kuwait

[6] Univ Malaysia Terengganu, Higher Inst Ctr Excellence HICoE, Inst Trop Aquaculture & Fisheries AKUATROP, Kuala Nerus 21030, Terengganu, Malaysia

[7] SRUC, Biorefining & Adv Mat Res Ctr, Kings Bldg,West Mains Rd, Edinburgh EH9 3JG, Midlothian, Scotland

[8] SRUC, Ctr Safe & Improved Food, Kings Bldg,West Mains Rd, Edinburgh EH9 3JG, Midlothian, Scotland

来源：

TRENDS IN BIOTECHNOLOGY | 2023年 / 41卷 / 06期

关键词：

DEACETYLATED CHITINS CHITOSANS; FIELD NMR-SPECTROSCOPY; ANTIBACTERIAL ACTIVITY; MOLECULAR-WEIGHT; CHITOOLIGOSACCHARIDE MIXTURE; SIRNA DELIVERY; N-ACETYLATION; OLIGOSACCHARIDES; NANOPARTICLES; EFFICIENCY;

D O I：

10.1016/j.tibtech.2022.11.009

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Chitosan, an amino polysaccharide mostly derived from crustaceans, has been recently highlighted for its biological activities that depend on its molecular importantly, for some advanced biomaterials, the homogeneity of the chitosan structure is an important factor in determining its biological activity. Here we review emerging enzymes and cell factories, respectively, for in vitro and in vivo preparation of chitosan oligosaccharides (COSs), focusing on advances in the analysis of the AP and structural modification of chitosan to tune its functions. By 'mapping' current knowledge on chitosan's in vitro and in vivo activity with its MW and AP, this work could pave the way for future studies in the field.

引用

页码：785 / 797

页数：13

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