Tuning sensitivity of bimetallic, MXene and graphene-based SPR biosensors for rapid malaria detection: a numerical approach

被引:74
作者
Karki, Bhishma [1 ,2 ,3 ,4 ]
Uniyal, Arun [5 ]
Sharma, Manoj [6 ]
Yadav, Ram Bharos [7 ]
Buduma, Parusharamulu [8 ]
机构
[1] Tribhuvan Univ, Dept Phys, Trichandra Multiple Campus, Kathmandu 44600, Nepal
[2] Natl Res Council Nepal, New Baneshwor 10, Kathmandu 44600, Nepal
[3] Tuljaram Chaturchand Coll Baramati, Dept Phys, Pune 413102, India
[4] Tuljaram Chaturchand Coll Baramati, Res Ctr, Pune 413102, India
[5] Uttarakhand Tech Univ, Inst Technol Gopeshwar, Dept Elect & Commun Engn, Campus Inst VMSB, Chamoli 246424, Uttarakhand, India
[6] Bharati Vidyapeeths Coll Engn, New Delhi 110063, India
[7] GB Pant Inst Engn & Technol, Dept Elect & Commun Engn, Pauri Garhwal 246194, Uttarakhand, India
[8] Lendi Inst Engn & Technol, Vizianagaram 535005, Andhra Pradesh, India
关键词
Malaria detection; SPR sensor; Sensitivity tuning; BK7; prism; SENSOR;
D O I
10.1007/s10825-024-02191-4
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The potential of surface plasmon resonance (SPR) biosensors to detect different biomolecules quickly and sensitively has attracted much attention. In this work, we use a numerical method to identify malaria phases by exploring the sensitivity adjustment of SPR sensors based on bimetallic, MXene and graphene layers. Effective treatment for malaria, a potentially fatal disease brought on by plasmodium parasites, depends on early identification. Innovative biosensing technologies are necessary since traditional diagnostic procedures frequently lack sensitivity and speed. The transfer matrix method is employed here in this study for reflectance calculation. The COMSOL software finds the electric field distribution across the various layers interfaces. The maximum sensitivity of 301.1667 degrees/RIU has been attained for the proposed work.
引用
收藏
页码:920 / 929
页数:10
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