A comprehensive review of lncRNA CRNDE in cancer progression and pathology, with a specific glance at the epithelial-mesenchymal transition (EMT) process

被引：2

作者：

Jasim, Saade Abdalkareem ^{[1
]}

Al-Hawary, Sulieman Ibraheem Shelash ^{[2
,13
]}

Hjazi, Ahmed ^{[3
]}

Ahmad, Irfan ^{[4
]}

Kaur, Irwanjot ^{[5
,6
]}

Kadhum, Wesam R. ^{[7
,8
]}

Alkhafaji, Adnan Taan ^{[9
]}

Ghildiyal, Pallavi ^{[10
]}

Jawad, Mohammed Abed ^{[11
]}

Alsaadi, Salim B. ^{[12
]}

机构：

[1] Al maarif Univ Coll, Med Lab Tech Dept, Anbar, Iraq

[2] Al Al Bayt Univ, Business Sch, Dept Business Adm, POB 130040, Mafraq 25113, Jordan

[3] Prince Sattam bin Abdulaziz Univ, Coll Appl Med Sci, Dept Med Lab, Al Kharj 11942, Saudi Arabia

[4] King Khalid Univ, Coll Appl Med Sci, Dept Clin Lab Sci, Abha, Saudi Arabia

[5] Jain Deemed to be Univ, Dept Biotechnol & Genet, Bengaluru 560069, Karnataka, India

[6] Vivekananda Global Univ, Dept Allied Healthcare & Sci, Jaipur 303012, Rajasthan, India

[7] Kut Univ Coll, Dept Pharm, Kut 52001, Wasit, Iraq

[8] Kut Univ Coll, Adv Res Ctr, Kut 52001, Wasit, Iraq

[9] Al Ayen Univ, Coll Med, Cardiol Dept, Thi Qar, Iraq

[10] Uttaranchal Univ, Uttaranchal Inst Pharmaceut Sci, Dehra Dun, India

[11] Al Nisour Univ Coll, Dept Pharmaceut, Baghdad, Iraq

[12] Al Hadi Univ Coll, Dept Pharmaceut, Baghdad 10011, Iraq

[13] Al Al Bayt Univ, Business Sch, Dept Business Adm, Business Management, POB130040, Mafraq 25113, Jordan

来源：

PATHOLOGY RESEARCH AND PRACTICE | 2024年 / 256卷

关键词：

CRNDE; Cancer progression; Epithelial-mesenchymal transition; Long noncoding RNA; LONG-NONCODING RNA; PROMOTES CELL-PROLIFERATION; COMPETING ENDOGENOUS RNA; GLIOMA STEM-CELLS; COLORECTAL-CANCER; OXALIPLATIN RESISTANCE; PROGNOSTIC VALUE; INVASION; EXPRESSION; CHEMOTHERAPY;

D O I：

10.1016/j.prp.2024.155229

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

It has been suggested that the long non-coding RNAs (lncRNAs), such as colorectal neoplasia differentially expressed (CRNDE), may contribute to the formation of human cancer. It is yet unknown, though, what therapeutic significance CRNDE expression has for different forms of cancer. CRNDE has recently been proposed as a possible diagnostic biomarker and prognostic pred for excellent specificity and sensitivity in cancer tissues and plasma. To provide the groundwork for potential future therapeutic uses of CRNDE, we briefly overview its biological action and related cancer-related pathways. Next, we mainly address the impact of CRNDE on the epithelial-mesenchymal transition (EMT). The epithelial-mesenchymal transition, or EMT, is an essential biological mechanism involved in the spread of cancer.

引用

页数：11

共 131 条

[1] Signaling pathways and microRNAs, the orchestrators of NANOG activity during cancer induction [J].

Alemohammad, Hajar ;

Asadzadeh, Zahra ;

Azad, Rohollah Motafakker ;

Hemmat, Nima ;

Najafzadeh, Basira ;

Vasefifar, Parisa ;

Najafi, Souzan ;

Baradaran, Behzad .

LIFE SCIENCES, 2020, 260

[2] The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence [J].

Auffinger, Brenda ;

Spencer, Drew ;

Pytel, Peter ;

Ahmed, Atique U. ;

Lesniak, Maciej S. .

EXPERT REVIEW OF NEUROTHERAPEUTICS, 2015, 15 (07) :741-752

[3] Global analysis of biogenesis, stability and sub-cellular localization of lncRNAs mapping to intragenic regions of the human genome [J].

Ayupe, Ana C. ;

Tahira, Ana C. ;

Camargo, Lauren ;

Beckedorff, Felipe C. ;

Verjovski-Almeida, Sergio ;

Reis, Eduardo M. .

RNA BIOLOGY, 2015, 12 (08) :877-892

[4] Hypermethylation of MGMT Gene Promoter in Peripheral Blood Mononuclear Cells as a Noninvasive Biomarker for Colorectal Cancer Diagnosis [J].

Azhdari, Sara ;

Khodabandehloo, Fatemeh ;

Ehtesham, Naeim ;

Mazhari, Seyed Amirhossein ;

Behroozi, Javad ;

Siri, Goli .

ADVANCED BIOMEDICAL RESEARCH, 2023, 12 (01) :256

[5] LncRNA CRNDE acts as an oncogene in cervical cancer through sponging miR-183 to regulate CCNB1 expression [J].

Bai, Xiaoxia ;

Wang, Wendong ;

Zhao, Peng ;

Wen, Jie ;

Guo, Xuedong ;

Shen, Tao ;

Shen, Junhua ;

Yang, Xiaofu .

CARCINOGENESIS, 2020, 41 (01) :111-121

[6] Genome-Wide Characterization of RNA Editing Sites in Primary Gastric Adenocarcinoma through RNA-seq Data Analysis [J].

Behroozi, Javad ;

Shahbazi, Shirin ;

Bakhtiarizadeh, Mohammad Reza ;

Mahmoodzadeh, Habibollah .

INTERNATIONAL JOURNAL OF GENOMICS, 2020, 2020

[7] ADAR expression and copy number variation in patients with advanced gastric cancer [J].

Behroozi, Javad ;

Shahbazi, Shirin ;

Bakhtiarizadeh, Mohammad Reza ;

Mahmoodzadeh, Habibollah .

BMC GASTROENTEROLOGY, 2020, 20 (01)

[8] Circular RNA Complement Factor H (CFH) Promotes Glioma Progression by Sponging miR-149 and Regulating AKT1 [J].

Bian, Aimiao ;

Wang, Yanping ;

Liu, Ji ;

Wang, Xiaodong ;

Liu, Dai ;

Jiang, Jian ;

Ding, Lianshu ;

Hui, Xiaobo .

MEDICAL SCIENCE MONITOR, 2018, 24 :5704-5712

[9] CTDNA AS A NOVEL AND PROMISING APPROACH FOR CANCER DIAGNOSIS: A FOCUS ON HEPATOCELLULAR CARCINOMA [J].

Biglari, Negin ;

Soltani-Zangbar, Mohammad Sadegh ;

Mohammadian, Jamal ;

Mehdizadeh, Amir ;

Abbasi, Khadijeh .

EXCLI JOURNAL, 2023, 22 :752-780

[10] Vascular mimicry: A potential therapeutic target in breast cancer [J].

Chavoshi, Hadi ;

Poormolaie, Neda ;

Vahedian, Vahid ;

Kazemzadeh, Hamid ;

Mir, Amirabbas ;

Nejabati, Hamid Reza ;

Behroozi, Javad ;

Isazadeh, Alireza ;

Hajezimian, Saba ;

Nouri, Mohammad ;

Maroufi, Nazila Fathi .

PATHOLOGY RESEARCH AND PRACTICE, 2022, 234

← 1 2 3 4 5 6 7 8 9 10 →