Thermo-acoustic imaging based on heat absorption distribution

被引：0
|
作者：
Li Y. [1 ,2 ]
Liu G. [1 ,2 ]
Song J. [1 ,2 ]
Xia H. [1 ]
机构：
[1] Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing
[2] University of Chinese Academy of Sciences, Beijing
来源：
Zhongguo Kexue Jishu Kexue/Scientia Sinica Technologica | 2019年 / 49卷 / 06期
关键词：
Bone; Heat absorption distribution; In vitro tissue; Low conductivity; Pulse current; Thermo-acoustic imaging;
D O I：
10.1360/N092018-00315
中图分类号：
学科分类号：
摘要：
Thermo-acoustic imaging with the current injection is a novel coupling imaging technology with electromagnetic field and sound field. It combines the advantages of high contrast of the electrical impedance tomography and the high spatial resolution of sonography, and then it has the potential of early diagnosis. In order to verify the feasibility of thermo-acoustic imaging with the current injection for complicated biological tissues, the principle of thermo-acoustic imaging with the current injection was analyzed. By injecting pulse current to phantom through a pair of electrodes, the joule heating is produced inside the objects and an acoustic signal is excited due to heat expansion. Heat absorption is considered thermo-acoustic source, the complex geometric model with low electrical conductivity was established, and the acoustic source and acoustic pressure distribution were obtained by coupling analysis of electromagnetic field and acoustic field. Meanwhile experimental system was established, and the experiments were carried out aiming at animal bone and fresh pork liver which are combined with low conductivity gel phantom (1, 0.5 S/m). The acoustic signal was detected by ultrasonic transducer with the center frequency of 1 MHz, and then the acoustic pressure and B-scan image were obtained. The results indicate that the B-scan image of thinner bone experiment can reflect the distribution of object accurately. Although the hard bone has a certain attenuation effect on the acoustic signal, a clear image can still be obtained, and the images can reflect the change of the conductivity of the gel. The experiment results of fresh pork liver show that this method can response the conductivity changes of low electrical conductivity biological tissue. This study confirms the feasibility of thermo-acoustic imaging with the current injection for the imaging of complex biological tissue. The novel method provides further evidence that it can be used for the diagnosis of human diseases. © 2019, Science Press. All right reserved.
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页码：641 / 651
页数：10
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