Kidney Transplant Recipient With Cerebral Paradoxical Embolism Following Recurrent Idiopathic Deep Vein Thrombosis and Pulmonary Embolism: Case Report and Review of the Literature

被引：0

作者：

Gheith, Osama ^{[1
,2
]}

Atya, Hassanen Abo ^{[1
]}

Nagib, Ayman Maher ^{[1
,2
]}

Sami, Ahmed ^{[1
]}

Nair, Prasad ^{[1
]}

Alawady, Medhat ^{[1
]}

Sharfuddin, Khaja M. ^{[3
]}

Fathy, Ahmed ^{[1
]}

Mattar, Wesam ^{[4
]}

Abass, Ahmed ^{[1
,5
]}

Mahmoud, Abdulwahab ^{[1
]}

Al Ajmi, Mohamed ^{[1
]}

Al Otaibi, Torki ^{[1
]}

机构：

[1] Hamed Alessa Organ Transplant Ctr, Nephrol Dept, Kuwait, Kuwait

[2] Mansoura Univ, Urol Nephrol Ctr, Dept Dialysis & Transplantat, Mansoura, Egypt

[3] Ibn Sina Hosp, Neurol Dept, Sabah Area, Kuwait, Kuwait

[4] Sabah Area, Radiol Dept, Kuwait, Kuwait

[5] Zagazig Univ, Chest Dept, Zagazig, Egypt

来源：

EXPERIMENTAL AND CLINICAL TRANSPLANTATION | 2024年 / 22卷 / 01期

关键词：

Bubble echocardiography; Renal transplant; Spontaneous venous thromboembolism; CRYPTOGENIC STROKE; ISCHEMIC-STROKE; PREVALENCE;

D O I：

10.6002/ect.MESOT2023.P38

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

Paradoxical embolism occurs when a thrombus crosses an intracardiac defect into the systemic circulation. Here, we present the case of a 35-year-old male kidney transplant recipient with a cerebral paradoxical embolism associated with a spontaneous venous thromboembolism. This patient had recurrent deep venous thrombosis and showering emboli to the lung and paradoxically to the brain through patent foramen ovale, and we treated him successfully. The role of bubble echocardiography was essential in diagnosis to avoid contrast-induced nephropathy. This is the first successfully managed case of a kidney transplant recipient with recurrent idiopathic deep vein thrombosis, pulmonary embolism, and cerebral paradoxical embolism. Bubble echocardiography was an excellent alternative to contrast angiography to avoid nephrotoxicity. Vitamin K antagonists are superior to direct oral anticoagulants, especially among nonadherent/noncompliant patients.

引用

页码：348 / 353

页数：6