A Mild and Metal Free Effective Route for the Synthesis of the Benzofuro[3,2-c]quinoline Frame Work via Pictet-Spengler Reaction

被引：0

作者：

Vanga, Anusha ^{[1
]}

Subbarao, Muppidi ^{[1
]}

Debbarma, Chumui ^{[2
]}

Nayak, Mrutunjay ^{[2
]}

Kamireddy, Kamalakar Reddy ^{[1
]}

Shiva Kumar, K. ^{[1
,2
]}

机构：

[1] Osmania Univ, Dept Chem, Hyderabad 500007, India

[2] Cent Univ Kerala, Sch Phys Sci, Dept Chem, Kasaragod 671316, Kerala, India

来源：

CHEMISTRYSELECT | 2024年 / 9卷 / 16期

关键词：

Benzofuro[3,2-c]quinoline; Pictet-Spengler Reaction; TFA; Metal free reaction; Atom economy; ASYMMETRIC-SYNTHESIS; HETEROCYCLES; POT; ISOCRYPTOLEPINE; CONSTRUCTION; CYCLIZATION; INHIBITION;

D O I：

10.1002/slct.202304296

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have reported an effective, metal free, one-pot methodology for synthesising benzofuro[3,2-c]quinolines via a Pictet-Spengler reaction under mild conditions in open air. Our approach has a few advantages over the traditional two-component synthesis as it is step and atom economic, environmentally benign and a convergent synthetic method. We have discussed here the good substrate scope of this novel methodology.

引用

页数：5

共 44 条

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