Overview of Radiation Therapy in the Management of Localized and Metastatic Prostate Cancer

被引:2
作者
Mattes, Malcolm D. [1 ]
机构
[1] Rutgers Canc Inst New Jersey, Dept Radiat Oncol, 195 Little Albany St, New Brunswick, NJ 08901 USA
关键词
Radiation therapy; Prostate cancer; Dose fractionation; Stereotactic body radiotherapy; Intensity modulated radiotherapy; Quality of life; ANDROGEN-DEPRIVATION THERAPY; INTENSITY-MODULATED RADIOTHERAPY; EXTERNAL-BEAM RADIOTHERAPY; QUALITY-OF-LIFE; PHASE-III TRIAL; STEREOTACTIC BODY RADIOTHERAPY; RATE BRACHYTHERAPY MONOTHERAPY; DECIPHER GENOMIC CLASSIFIER; LOCALLY ADVANCED CANCER; RADICAL PROSTATECTOMY;
D O I
10.1007/s11934-024-01217-5
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose of ReviewThe goal is to describe the evolution of radiation therapy (RT) utilization in the management of localized and metastatic prostate cancer.Recent FindingsLong term data for a variety of hypofractionated definitive RT dose-fractionation schemes has matured, allowing patients and providers many standard-of-care options to choose from. Post-prostatectomy, adjuvant RT has largely been replaced by an early salvage approach. Multiparametric MRI and PSMA PET have enabled increasingly targeted RT delivery to the prostate and oligometastatic tumors. Areas of active investigation include determining the value of proton beam therapy and perirectal spacers, and optimally incorporate genomic tumor profiling and next generation hormonal therapies with RT in the curative setting.SummaryThe use of radiation therapy to treat prostate cancer is rapidly evolving. In the coming years, there will be continued improvements in a variety of areas to enhance the value of RT in multidisciplinary prostate cancer management.
引用
收藏
页码:181 / 192
页数:12
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