Perdurable PD-1 blockage awakes anti-tumor immunity suppressed by precise chemotherapy

被引：0
|
作者：
Jiang, Mengshi [1 ]
Li, Wei [2 ]
Zhu, Chunqi [1 ]
Li, Xiang [1 ]
Zhang, Junlei [1 ]
Luo, Zhenyu [1 ]
Qin, Bing [1 ]
Du, Yongzhong [1 ]
Luo, Lihua [1 ]
You, Jian [1 ]
机构：
[1] College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou,Zhejiang,310058, China
[2] Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas,TX,75390, United States
来源：
Journal of Controlled Release | 2021年 / 329卷
基金：
中国国家自然科学基金;
关键词：
Targeted drug delivery - Hyaluronic acid - Cancer cells - Cytology - Micelles - Diseases - Drug interactions - Tumors - Controlled drug delivery - Covalent bonds - Immune system - Pathology - Sulfur compounds - Drug dosage - Cells;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1023 / 1036
相关论文
共 50 条
  • [21] Anti-tumor effects of genetic deletion of PD-1 in adult mice
    Raghavan, Sukaya
    Tovbis, Nataliya Shifrin
    Kochel, Christina
    Malefyt, Rene deWaal
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2017, 86 (04) : 339 - 340
  • [22] Anlotinib optimizes anti-tumor innate immunity to potentiate the therapeutic effect of PD-1 blockade in lung cancer
    Yinli Yang
    Ling Li
    Zhansheng Jiang
    Bin Wang
    Zhanyu Pan
    Cancer Immunology, Immunotherapy, 2020, 69 : 2523 - 2532
  • [23] PD-1 and IL-10: partners in crime against anti-tumor immunity in ovarian cancer.
    Lamichhane, Purushottam
    Karyampudi, Lavakumar
    Shreeder, Barath
    Knutson, Keith
    JOURNAL OF IMMUNOLOGY, 2015, 194
  • [24] PD-1 directly suppresses macrophage metabolism to restrict anti-tumor immunity in an obesity-cancer connection
    Bader, Jackie
    Rathmell, Jeffrey
    CANCER RESEARCH, 2024, 84 (06)
  • [25] Anlotinib optimizes anti-tumor innate immunity to potentiate the therapeutic effect of PD-1 blockade in lung cancer
    Yang, Yinli
    Li, Ling
    Jiang, Zhansheng
    Wang, Bin
    Pan, Zhanyu
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2020, 69 (12) : 2523 - 2532
  • [26] SAA suppresses α-PD-1 induced anti-tumor immunity by driving TH2 polarization in lung adenocarcinoma
    Wang, Xin
    Wen, Shaodi
    Du, Xiaoyue
    Zhang, Yihan
    Yang, Xiao
    Zou, Renrui
    Feng, Bing
    Fu, Xiao
    Jiang, Feng
    Zhou, Guoren
    Liu, Zi
    Zhu, Wei
    Ma, Rong
    Feng, Jifeng
    Shen, Bo
    CELL DEATH & DISEASE, 2023, 14 (11)
  • [27] Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
    Sakuishi, Kaori
    Apetoh, Lionel
    Sullivan, Jenna M.
    Blazar, Bruce R.
    Kuchroo, Vijay K.
    Anderson, Ana C.
    JOURNAL OF EXPERIMENTAL MEDICINE, 2010, 207 (10): : 2187 - 2194
  • [28] SAA suppresses α-PD-1 induced anti-tumor immunity by driving TH2 polarization in lung adenocarcinoma
    Xin Wang
    Shaodi Wen
    Xiaoyue Du
    Yihan Zhang
    Xiao Yang
    Renrui Zou
    Bing Feng
    Xiao Fu
    Feng Jiang
    Guoren Zhou
    Zi Liu
    Wei Zhu
    Rong Ma
    Jifeng Feng
    Bo Shen
    Cell Death & Disease, 14
  • [29] Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells
    Okada, Masahiro
    Chikuma, Shunsuke
    Kondo, Taisuke
    Hibino, Sana
    Machiyama, Hiroaki
    Yokosuka, Tadashi
    Nakano, Miyako
    Yoshimura, Akihiko
    CELL REPORTS, 2017, 20 (05): : 1017 - 1028
  • [30] Combination of lentivector immunization and low-dose chemotherapy or PD-1/PD-L1 blocking primes self-reactive T cells and induces anti-tumor immunity
    Sierro, Sophie R.
    Donda, Alena
    Perret, Rachel
    Guillaume, Philippe
    Yagita, Hideo
    Levy, Frederic
    Romero, Pedro
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2011, 41 (08) : 2217 - 2228
12345