Hypoxia-responsive immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy for potentiating cancer immunotherapy

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作者
Chen, Weiguo [1 ]
Sheng, Ping [1 ]
Chen, Yujiang [1 ]
Liang, Yi [1 ]
Wu, Sixin [1 ]
Jia, Liying [1 ]
He, Xin [2 ]
Zhang, Chunfeng [1 ]
Wang, Chongzhi [3 ]
Yuan, Chunsu [3 ]
机构
[1] School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing,210009, China
[2] School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong
[3] Tang Center of Herbal Medicine Research and Department of Anesthesia & Critical Care, University of Chicago, IL, Chicago,60637, United States
关键词
Anti-tumor immune - Anticancer activities - Cancer immunotherapy - Celastrols - Covalent organic frameworks - Hydroxycamptothecin - Immune response - Immunogenic cell death - Immunogenic nanomedicine - Physicochemical property;
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