Recent advances in the diagnosis of drug-induced liver injury

被引：4

作者：

Ahmed, Taqwa ^{[1
]}

Ahmad, Jawad ^{[2
]}

机构：

[1] Icahn Sch Med Mt Sinai, Dept Med, New York, NY 10029 USA

[2] Icahn Sch Med Mt Sinai, Miller Transplantat Inst, Dept Recanati, One Gustave L Levy Pl, New York, NY 10029 USA

来源：

WORLD JOURNAL OF HEPATOLOGY | 2024年 / 16卷 / 02期

关键词：

Drug induced liver injury; Liver biopsy; Diagnosis; RUCAM; RECAM; CAUSALITY ASSESSMENT;

D O I：

10.4254/wjh.v16.i2.186

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Drug-induced liver injury (DILI) is a major problem in the United States, commonly leading to hospital admission. Diagnosing DILI is difficult as it is a diagnosis of exclusion requiring a temporal relationship between drug exposure and liver injury and a thorough work up for other causes. In addition, DILI has a very variable clinical and histologic presentation that can mimic many different etiologies of liver disease. Objective scoring systems can assess the probability that a drug caused the liver injury but liver biopsy findings are not part of the criteria used in these systems. This review will address some of the recent updates to the scoring systems and the role of liver biopsy in the diagnosis of DILI.

引用

页码：186 / 192

页数：8

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