The effect of education regarding treatment guidelines for schizophrenia and major depressive disorders on psychiatrists' hypnotic medication prescribing behavior: a multicenter study

被引：0

作者：

Nakamura, Toshinori ^{[1
]}

Furihata, Ryuji ^{[2
]}

Hasegawa, Naomi ^{[3
]}

Kodaka, Fumitoshi ^{[3
,4
]}

Muraoka, Hiroyuki ^{[5
]}

Ichihashi, Kayo ^{[6
]}

Ochi, Shinichiro ^{[7
]}

Numata, Shusuke ^{[8
]}

Tsuboi, Takashi ^{[9
]}

Makinodan, Manabu ^{[10
]}

Iida, Hitoshi ^{[11
]}

Onitsuka, Toshiaki ^{[12
]}

Kashiwagi, Hiroko ^{[3
,13
]}

Takeshima, Masahiro ^{[14
]}

Hashimoto, Naoki ^{[15
]}

Nagasawa, Tatsuya ^{[16
]}

Usami, Masahide ^{[17
]}

Yamagata, Hirotaka ^{[3
,18
]}

Takaesu, Yoshikazu ^{[19
]}

Miura, Kenichiro ^{[3
]}

Matsumoto, Junya ^{[3
]}

Ohi, Kazutaka ^{[20
]}

Yamada, Hisashi ^{[3
,21
]}

Hori, Hikaru ^{[11
]}

Inada, Ken ^{[5
]}

Watanabe, Koichiro ^{[9
]}

Hashimoto, Ryota ^{[3
]}

Yasui-Furukori, Norio ^{[22
]}

机构：

[1] Shinshu Univ, Sch Med, Dept Pathol, 3-1-1 Asahi, Matsumoto 3908621, Japan

[2] Kyoto Univ, Agcy Student Support & Disabil Resources, Yoshida Honmachi, Kyoto 6068501, Japan

[3] Natl Ctr Neurol & Psychiat, Natl Inst Mental Hlth, Dept Publ Mental Hlth Res, 4-1-1 Ogawahigashi, Kodaira 1878553, Japan

[4] Jikei Univ, Sch Med, Dept Psychiat, 3-18-13 Nishi Shinbashi, Minato 1058471, Japan

[5] Kitasato Univ, Sch Med, Dept Psychiat, 1-15-1 Kitazato, Sagamihara 2520373, Japan

[6] Univ Tokyo Hosp, Dept Neuropsychiat, 7-3-1 Hongo, Tokyo 1138655, Japan

[7] Ehime Univ, Grad Sch Med, Dept Neuropsychiat Mol & Funct, Shitsukawa, Toon 7910295, Japan

[8] Tokushima Univ, Grad Sch Biomed Sci, Dept Psychiat, 3-8-15 Kuramoto Cho, Tokushima 7708503, Japan

[9] Kyorin Univ, Sch Med, Dept Neuropsychiat, 6-20-2 Shinkawa, Mitaka 1818611, Japan

[10] Nara Med Univ, Dept Psychiat, 840 Shijo Cho, Kashihara 6348522, Japan

[11] Fukuoka Univ, Fac Med, Dept Psychiat, 7-45-1 Nanakuma, Fukuoka 8140180, Japan

[12] NHO Sakakibara Natl Hosp, 777 Sakakibara Cho, Tsu 5141292, Japan

[13] Natl Ctr Psychiat & Neurol, Natl Ctr Hosp, Dept Forens Psychiat, 4-1-1 Ogawahigashi, Kodaira 1878551, Japan

[14] Akita Univ, Grad Sch Med, Dept Neuropsychiat, 1-1-1 Hondo, Akita 0108543, Japan

[15] Hokkaido Univ, Grad Sch Med, Dept Psychiat, Kita 15,Nishi 7, Sapporo 0608638, Japan

[16] Kanazawa Med Univ, Dept Neuropsychiat, 1-1 Daigaku, Uchinada 9200293, Japan

[17] Natl Ctr Global Hlth & Med, Kohnodai Hosp, Dept Child & Adolescent Psychiat, 1-7-1 Kohnodai, Ichikawa 2728516, Japan

[18] Kokoro Hosp Machida, 2140 Kamioyamadamachi, Machida, Japan

[19] Univ Ryukyus, Grad Sch Med, Dept Neuropsychiat, 207 Uehara, Nishihara 9030215, Japan

[20] Gifu Univ, Grad Sch Med, Dept Psychiat, 1-1 Yanagido, Gifu 5011194, Japan

[21] Hyogo Med Univ, Dept Neuropsychiat, 1-1 Mukogawa Cho, Nishinomiya 6638501, Japan

[22] Dokkyo Med Univ, Sch Med, Dept Psychiat, 880 Kitakobayashi, Mibu 3210293, Japan

来源：

BMC PSYCHIATRY | 2024年 / 24卷 / 01期

关键词：

Clinical practice guideline; Psychiatrist; Hypnotic medication; Schizophrenia; Major depressive disorders; BIOLOGICAL TREATMENT; WFSBP GUIDELINES; WORLD FEDERATION; SLEEP; SOCIETIES; RISK;

D O I：

10.1186/s12888-024-05816-x

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Background To examine whether the "Effectiveness of Guideline for Dissemination and Education in psychiatric treatment (EGIUDE)" project affects the rate of prescriptions of hypnotic medication and the type of hypnotic medications prescribed among psychiatrists, for schizophrenia and major depressive disorder in Japan. Methods The EGUIDE project is a nationwide prospective study of evidence-based clinical guidelines for schizophrenia and major depressive disorder in Japan. From 2016 to 2021, clinical and prescribing data from patients discharged from hospitals participating in the EGUIDE project were used to examine hypnotic medication prescriptions The prescribing rate of hypnotics and the prescribing rate of each type of hypnotic (benzodiazepine receptor agonist, nonbenzodiazepine receptor agonist, melatonin receptor agonist, and orexin receptor antagonist) were compared among patients who had been prescribed medication by psychiatrists participating in the EGUIDE project and patients who had been prescribed medication by nonparticipating psychiatrists. Multivariate logistic regression analysis was performed to examine the effect of the EGUIDE project on the prescription of hypnotic medications. Results A total of 12,161 patients with schizophrenia and 6,167 patients with major depressive disorder were included. Psychiatrists participating in the EGUIDE project significantly reduced the rate of prescribing hypnotic medication and benzodiazepine receptor agonists for both schizophrenia (P < 0.001) and major depressive disorder (P < 0.001) patients. Conclusion This is the first study to investigate the educational effects of guidelines for the treatment of psychiatric disorders on psychiatrists in terms of prescribing hypnotic medications to patients. The EGUIDE project may play an important role in reducing hypnotic medication prescription rates, particularly with respect to benzodiazepine receptor agonists. The results suggest that the EGUIDE project may result in improved therapeutic behavior.

引用

页数：10

共 35 条

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