Current state of research on exercise for the treatment of myasthenia gravis: A scoping review

被引：0

作者：

Peng, Siyang ^{[1
]}

Meng, Linghao ^{[1
]}

Fang, Ruiying ^{[1
]}

Shen, Qiqi ^{[1
]}

Tian, Yukun ^{[1
]}

Xiong, Anni ^{[1
]}

Li, Shaohong ^{[2
]}

Yang, Yajing ^{[3
]}

Chang, Weiqian ^{[4
]}

Ni, Jinxia ^{[5
]}

Zhu, Wenzeng ^{[1
,6
]}

机构：

[1] Guanganmen Hosp, China Acad Chinese Med Sci, Dept Acupuncture, Beijing, Peoples R China

[2] Beijing Boai Hosp, Treatment Ctr Tradit Chinese Med, China Rehabil Res Ctr, Beijing, Peoples R China

[3] Yuyuantan Community Hlth Ctr, Dept Tradit Chinese Med, Beijing, Peoples R China

[4] Jinan Hosp Tradit Chinese Med, Jinan Hosp, Chinese Acad Tradit Chinese Med, Dept Acupuncture,Guanganmen Hosp, Jinan, Shandong, Peoples R China

[5] Beijing Univ Tradit Chinese Med, Dongzhimen Hosp, Dept Acupuncture, Beijing, Peoples R China

[6] 5 Beixiange, Beijing, Peoples R China

来源：

COMPLEMENTARY THERAPIES IN MEDICINE | 2024年 / 81卷

关键词：

Myasthenia gravis; Exercise; Efficacy; Safety; Scoping review; PHYSICAL-EXERCISE; THERAPY; FEASIBILITY; GUIDELINES;

D O I：

10.1016/j.ctim.2024.103033

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Objective: To provide a comprehensive overview of existing evidence, research gaps, and future research priorities concerning the treatment of myasthenia gravis (MG) using exercise therapies. Method: Clinical studies on exercise treatment for MG were searched in nine databases to conduct a scoping review. Two independent researchers screened the literature and comprehensively analyzed the characteristics and limitations of the included articles. Results: A total of 5725 studies were retrieved, of which 24 were included. The included studies were conducted in 16 different countries/regions and 456 patients were enrolled. Study designs included both interventional and observational studies. Exercise interventions included aerobic exercise, resistance exercise, balance training, and stretch training, and are typically administered in conjunction with medication, usual care, or some other interventions. The intensity, frequency, and duration of exercise interventions varied hugely among studies. Sixminute walk test, adverse events, muscle strength, MG quality of life-15 scale, forced vital capacity, quantitative MG scale, and MG activities of daily living scale were the most frequently used outcomes. All studies reported results in favor of the efficacy and safety of exercise in MG, and exercise-related adverse events were reported in two studies. Conclusion: This scoping review provides an overview of the evidence concerning exercise treatment for MG. Key gaps in evidence include a limited number of participants, complex interventions, variability in outcome selection, and insufficient reporting in publications. The promotion of exercise treatment for MG still encounters several obstacles. A larger population, rigorous study design and conduction, standardized interventions and outcomes, and standardized reporting are essential.

引用

页数：9