Effects of Transcatheter Aortic Valve Implantation on Frailty and Quality of Life

被引：8
作者：
Gouda, Pishoy [1 ,2 ]
Paterson, Chai [1 ,2 ]
Meyer, Steven [1 ,2 ]
Shanks, Miriam [1 ,2 ]
Butler, Craig [1 ,2 ]
Taylor, Dylan [1 ,2 ]
Tyrrell, Benjamin [1 ,3 ]
Welsh, Robert [1 ,2 ]
机构：
[1] Univ Alberta, Edmonton, AB, Canada
[2] Mazankowski Alberta Heart Inst, WMC, 2C2 Cardiol,8440 112 St NW, Edmonton, AB T6G 2B7, Canada
[3] CK Hui Heart Ctr, Edmonton, AB, Canada
来源：
CJC OPEN | 2020年 / 2卷 / 03期
关键词：
D O I：
10.1016/j.cjco.2019.12.006
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background: Transcatheter aortic valve implantation (TAVI) is an effective alternative to surgical valve replacement in high-risk patients with severe aortic stenosis. Although measures of frailty have been used to attempt to predict outcomes in this population, few studies have demonstrated changes in these measures. Methods: We performed a prospective, observational study of 171 patients undergoing TAVI, of whom 44 had maximal follow-up of 1 month and 50 had maximal follow-up of 1 year. Quality of life was assessed using the Minnesota Living With Heart Failure Questionnaire, Katz Index of Independence in Activities of Daily Living questionnaire,and patient perception of overall well-being. Frailty was measured using the 10-m walk test and handgrip strength testing. Results: In the overall cohort, participants demonstrated improvements in quality of life metrics, but deterioration in 10-m walk test and handgrip at 1 month. These trends continued at 1 year. However, patients in the lowest quintile of handgrip and 10-m walk test demonstrated a trend of improvements in these metrics during follow-up. Conclusions: Despite improvements in quality of life after TAVI, no improvements in frailty were observed in patients at 1 year.
引用
收藏
页码：79 / 84
页数：6
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