Healthy ageing and the kidney - lessons from centenarians

被引:1
作者
Arai, Yasumichi [1 ]
Yanagita, Motoko [2 ,3 ]
机构
[1] Keio Univ, Ctr Supercentenarian Med Resaerch, Sch Med, Tokyo, Japan
[2] Kyoto Univ, Grad Sch Med, Dept Nephrol, Kyoto, Japan
[3] Kyoto Univ, Inst Adv Study Human Biol ASHBi, Kyoto, Japan
关键词
D O I
10.1038/s41581-024-00860-y
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Centenarians - who are a putative model of healthy longevity - often have a low risk of cardiovascular disease, despite an age-associated decline in kidney function. An understanding of the molecular and cellular underpinnings of health kidney ageing in centenarians may provide clues for the prevention or alleviation of the burden of kidney disease in older populations.
引用
收藏
页码:558 / 559
页数:2
相关论文
共 12 条
  • [1] Estimating glomerular filtration rate in centenarians: comparison of the chronic kidney disease epidemiology collaboration (CKD-EPI) and modification of diet in renal disease (MDRD) study equations
    Basile, Giorgio
    Crucitti, Andrea
    Fusco, Sergio
    Cucinotta, Maria D.
    Maltese, Giuseppe
    Catalano, Antonino
    Lasco, Antonino
    [J]. INTERNATIONAL UROLOGY AND NEPHROLOGY, 2014, 46 (02) : 481 - 482
  • [2] Cellular Senescence in the Kidney
    Docherty, Marie-Helena
    O'Sullivan, Eoin D.
    Bonventre, Joseph, V
    Ferenbach, David A.
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2019, 30 (05): : 726 - 736
  • [3] The practicality of different eGFR equations in centenarians and near-centenarians: which equation should we choose?
    Han, Qiuxia
    Zhang, Dong
    Zhao, Yali
    Liu, Liang
    Li, Jing
    Zhang, Fu
    Luan, Fuxin
    Duan, Jiayu
    Liu, Zhangsuo
    Cai, Guangyan
    Chen, Xiangmei
    Zhu, Hanyu
    [J]. PEERJ, 2020, 8
  • [4] Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen
    Hasegawa, Tatsuya
    Oka, Tomonori
    Son, Heehwa G.
    Oliver-Garcia, Valeria S.
    Azin, Marjan
    Eisenhaure, Thomas M.
    Lieb, David J.
    Hacohen, Nir
    Demehri, Shadmehr
    [J]. CELL, 2023, 186 (07) : 1417 - +
  • [5] Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians
    Hashimoto, Kosuke
    Kouno, Tsukasa
    Ikawa, Tomokatsu
    Hayatsu, Norihito
    Miyajima, Yurina
    Yabukami, Haruka
    Terooatea, Tommy
    Sasaki, Takashi
    Suzuki, Takahiro
    Valentine, Matthew
    Pascarella, Giovanni
    Okazaki, Yasushi
    Suzuki, Harukazu
    Shin, Jay W.
    Minoda, Aki
    Taniuchi, Ichiro
    Okano, Hideyuki
    Arai, Yasumichi
    Hirose, Nobuyoshi
    Carninci, Piero
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (48) : 24242 - 24251
  • [6] Associations of cardiovascular biomarkers and plasma albumin with exceptional survival to the highest ages
    Hirata, Takumi
    Arai, Yasumichi
    Yuasa, Shinsuke
    Abe, Yukiko
    Takayama, Michiyo
    Sasaki, Takashi
    Kunitomi, Akira
    Inagaki, Hiroki
    Endo, Motoyoshi
    Morinaga, Jun
    Yoshimura, Kimio
    Adachi, Tetsuo
    Oike, Yuichi
    Takebayashi, Toru
    Okano, Hideyuki
    Hirose, Nobuyoshi
    [J]. NATURE COMMUNICATIONS, 2020, 11 (01)
  • [7] Structural and Functional Changes in Human Kidneys with Healthy Aging
    Hommos, Musab S.
    Glassock, Richard J.
    Rule, Andrew D.
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2017, 28 (10): : 2838 - 2844
  • [8] Multiple cardiometabolic diseases enhance the adverse effects of hypoalbuminemia on mortality among centenarians in China: a cohort study
    Li, Haowei
    Wang, Shengshu
    Yang, Shanshan
    Liu, Shaohua
    Song, Yang
    Chen, Shimin
    Li, Xuehang
    Li, Zhiqiang
    Li, Rongrong
    Zhao, Yali
    Zhu, Qiao
    Ning, Chaoxue
    Liu, Miao
    He, Yao
    [J]. DIABETOLOGY & METABOLIC SYNDROME, 2023, 15 (01)
  • [9] CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury
    Sato, Yuki
    Oguchi, Akiko
    Fukushima, Yuji
    Masuda, Kyoko
    Toriu, Naoya
    Taniguchi, Keisuke
    Yoshikawa, Takahisa
    Cui, Xiaotong
    Kondo, Makiko
    Hosoi, Takeshi
    Komidori, Shota
    Shimizu, Yoko
    Fujita, Harumi
    Jiang, Li
    Kong, Yingyi
    Yamanashi, Takashi
    Seita, Jun
    Yamamoto, Takuya
    Toyokuni, Shinya
    Hamazaki, Yoko
    Hattori, Masakazu
    Yoshikai, Yasunobu
    Boor, Peter
    Floege, Juergen
    Kawamoto, Hiroshi
    Murakawa, Yasuhiro
    Minato, Nagahiro
    Yanagita, Motoko
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2022, 132 (02)
  • [10] AnatoMy and physIopathoLogy of the heArt in a ceNtenarian cOhort (MILANO study)
    Sonaglioni, Andrea
    Lombardo, Michele
    Batavelli, Massimo
    Vincenti, Antonio
    Rigamonti, Elisabetta
    Vanoli, Emilio
    Nicolosi, Gian Luigi
    Sommes, Carmen
    Anza, Claudio
    [J]. AMERICAN HEART JOURNAL, 2018, 205 : 12 - 20