Necrotizing enterocolitis in a term newborn after spontaneous cerebral parenchymal hemorrhage: a case report

被引:0
作者
Zhang, Lijuan [1 ]
Lu, Weifeng [1 ]
机构
[1] Nanjing Med Univ, Childrens Hosp, Dept Surg Intens Care Unit, 72 Guangzhou Rd, Nanjing 210008, Jiangsu, Peoples R China
关键词
Necrotizing enterocolitis; Spontaneous cerebral parenchymal hemorrhage; Term newborn; Brain-gut axis; MICROBIOTA; INFANTS;
D O I
10.1186/s12887-024-04866-0
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background Necrotizing enterocolitis (NEC) and intracranial hemorrhage are severe emergencies in the neonatal period. The two do not appear to be correlated. However, our report suggests that parenchymal brain hemorrhage in full-term newborns may put patients at risk for NEC by altering intestinal function through the brain-gut axis.Case presentation We present a case of spontaneous parenchymal cerebral hemorrhage in a full-term newborn who developed early-stage NEC on Day 15.Conclusions It is possible to consider brain parenchymal hemorrhage as a risk factor for the appearance of NEC. Clinicians should be highly cautious about NEC in infants who have experienced parenchymal hemorrhage. This article is the first to discuss the relationship between parenchymal hemorrhage and NEC in full-term newborns.
引用
收藏
页数:5
相关论文
共 22 条
  • [1] Necrotizing Enterocolitis Associated with Congenital Heart Disease: a Different Entity?
    Bubberman, J. M.
    van Zoonen, A.
    Bruggink, J. L. M.
    van der Heide, M.
    Berger, R. M. F.
    Bos, A. F.
    Kooi, E. M. W.
    Hulscher, J. B. F.
    [J]. JOURNAL OF PEDIATRIC SURGERY, 2019, 54 (09) : 1755 - 1760
  • [2] The interplay between the intestinal microbiota and the brain
    Collins, Stephen M.
    Surette, Michael
    Bercik, Premysl
    [J]. NATURE REVIEWS MICROBIOLOGY, 2012, 10 (11) : 735 - 742
  • [3] Stress induces endotoxemia and low-grade inflammation by increasing barrier permeability
    de Punder, Karin
    Pruimboom, Leo
    [J]. FRONTIERS IN IMMUNOLOGY, 2015, 6
  • [4] High dietary salt-induced DC activation underlies microbial dysbiosis-associated hypertension
    Ferguson, Jane F.
    Aden, Luul A.
    Barbaro, Natalia R.
    Van Beusecum, Justin P.
    Xiao, Liang
    Simons, Alan J.
    Warden, Cassandra
    Pasic, Lejla
    Himmel, Lauren E.
    Washington, Mary K.
    Revetta, Frank L.
    Zhao, Shilin
    Kumaresan, Shivani
    Scholz, Matthew B.
    Tang, Zhengzheng
    Chen, Guanhua
    Reilly, Muredach P.
    Kirabo, Annet
    [J]. JCI INSIGHT, 2019, 4 (13)
  • [5] Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production
    Houlden, A.
    Goldrick, M.
    Brough, D.
    Vizi, E. S.
    Lenart, N.
    Martinecz, B.
    Roberts, I. S.
    Denes, A.
    [J]. BRAIN BEHAVIOR AND IMMUNITY, 2016, 57 : 10 - 20
  • [6] Fecal microbiota transplantation inhibited neuroinflammation of traumatic brain injury in mice via regulating the gut-brain axis
    Hu, Xuezhen
    Jin, Hangqi
    Yuan, Shushu
    Ye, Tao
    Chen, Zhibo
    Kong, Yu
    Liu, Jiaming
    Xu, Kaihong
    Sun, Jing
    [J]. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2023, 13
  • [7] Surgical necrotizing enterocotitis and intraventricular hemorrhage in premature infants below 1000 g
    Jen, Howard C.
    Graber, Jerome J.
    Hill, J. Laurance
    Alaish, Samuel M.
    Voigt, Roger W.
    Strauch, Eric D.
    [J]. JOURNAL OF PEDIATRIC SURGERY, 2006, 41 (08) : 1425 - 1430
  • [8] A pilot study: Gut microbiota, metabolism and inflammation in hypertensive intracerebral haemorrhage
    Li, Wei
    Wu, Li-xiang
    Huang, Bai-sheng
    Yang, Li-jian
    Huang, Jun-qiang
    Li, Zeng-shi
    Jiao, Jia
    Cheng, Tianxiang
    Li, Ding
    Xiong, Yuanyuan
    [J]. JOURNAL OF APPLIED MICROBIOLOGY, 2022, 133 (02) : 972 - 986
  • [9] Necrotising enterocolitis
    Lin, Patricia W.
    Stoll, Barbara J.
    [J]. LANCET, 2006, 368 (9543) : 1271 - 1283
  • [10] Necrotizing enterocolitis in full-term infants: Case-control study and review of the literature
    Maayan-Metzger A.
    Itzchak A.
    Mazkereth R.
    Kuint J.
    [J]. Journal of Perinatology, 2004, 24 (8) : 494 - 499