Promising future: a review of clinical applications of biopolymers in renal cell carcinoma

被引:0
|
作者
Zhou, Xuan [1 ]
Xue, Kaming [2 ]
Xu, Ruifeng [3 ]
Li, Qingyi [3 ]
Huang, Furong [3 ]
Huang, Yongming [4 ]
Xiao, Wen [1 ]
Wang, Keshan [1 ]
Zhang, Xiaoping [1 ,5 ]
机构
[1] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Urol, 1277 Jiefang Ave, Wuhan 430022, Hubei, Peoples R China
[2] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Integrated Tradit Chinese & Western Med, Wuhan 430022, Hubei, Peoples R China
[3] Huazhong Univ Sci & Technol, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China
[4] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Gastrointestinal Surg, Wuhan 430030, Peoples R China
[5] Shenzhen Huazhong Univ Sci & Technol, Res Inst, Shenzhen 518063, Guangdong, Peoples R China
关键词
Renal cell carcinoma; kidney cancer; bioactive polymers; clinical application; DESORPTION/IONIZATION MASS-SPECTROMETRY; DRUG-DELIVERY SYSTEM; IN-VITRO; NANOPARTICLES; TISSUE; EXOSOMES; HYPOXIA; AGENT; TRIAL; COMBINATION;
D O I
10.20517/2394-4722.2024.12
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Renal cell carcinoma (RCC), being the most common type of renal malignancy, accounting for 85% of its incidence, poses a significant threat to human health. Although progress has been made in RCC diagnosis and management, problems of delayed detection and treatment failure remain in traditional methods. In the development of material research, biopolymers have emerged as significant players in medical practices, demonstrating considerable potential in the management of kidney cancer. Specifically, bioactive polymers have been proven to have numerous advantages over traditional methods, finding prosperous applications in diverse areas such as imaging detection, chemotherapy carrier, and prognostic estimation. However, the clinical value of some biopolymers still needs to be fully recognized in the RCC clinical pathway. This review summarizes recent studies about bioactive polymers' application in RCC and further discusses its significance and constraints in clinical translational medicine and clinical trials. As our understanding of biopolymers grows, more advancements can be carried out in clinical practices.
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页数:22
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