Renal Transplantation in Older Adults, an Updated Review

被引:1
作者
Black, Matthew W. [1 ]
Romine, Margaret M. [1 ]
Leeser, David B. [1 ]
机构
[1] East Carolina Univ, Floor 3 South,2100 Stantonsburg Rd, Greenville, NC 27834 USA
关键词
Older; Renal; Kidney; Transplant; Transplantation; DONOR KIDNEY-TRANSPLANTATION; ELDERLY-PATIENTS; LIVING DONOR; OUTCOMES; RECIPIENTS; FRAILTY; AGE;
D O I
10.1007/s40472-024-00438-4
中图分类号
R61 [外科手术学];
学科分类号
摘要
Purpose of ReviewThe purpose of this paper will be to review the most recent literature regarding renal transplantation in an older population. We aim to bring the reader up to date on this topic, and see what challenges are posed by transplanting this ever increasing population.Recent FindingsRenal transplantation in older adults is a continually evolving field. We review outcomes for older patients in remaining on dialysis, outcomes with living donors, outcomes vs younger patients, readmission, frailty, quality of life, immunosuppressant management, and our own centers experience.SummaryWe show, through various papers, that outcomes for older adults are better with receiving a kidney transplant than staying on dialysis. Outcomes for older recipients vs younger recipients are also acceptable, especially when one factors in death censored graft survival. Older patients also require special consideration to keep their readmission rate low, balance their immunosuppressant requirements, and correctly evaluate their frailty.
引用
收藏
页码:153 / 159
页数:7
相关论文
共 34 条
[1]   Kidney Transplantation in Elderly Recipients: A Single-Center Experience [J].
Adani, G. L. ;
Baccarani, U. ;
Crestale, S. ;
Pravisani, R. ;
Isola, M. ;
Tulissi, P. ;
Vallone, C. ;
Nappi, R. ;
Risaliti, A. .
TRANSPLANTATION PROCEEDINGS, 2019, 51 (01) :132-135
[2]   The clinical application of frailty in nephrology and transplantation [J].
Alsaad, Ranim ;
Chen, Xiaomeng ;
McAdams-DeMarco, Mara .
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2021, 30 (06) :593-599
[3]  
[Anonymous], 2023 ANN RE US ORG P
[4]   Assessing the Limits in Kidney Transplantation: Use of Extremely Elderly Donors and Outcomes in Elderly Recipients [J].
Arcos, Emma ;
Jose Perez-Saez, Maria ;
Comas, Jordi ;
Lloveras, Josep ;
Tort, Jaume ;
Pascual, Julio ;
Martinez-Castelao, Alberto ;
Troya, Maribel ;
Cases, Aleix ;
Calabia, Jordi ;
Cao, Higinio ;
Segarra, Alfons ;
Martinez-Vea, Alberto ;
Gil-Vernet, Salvador ;
Espinel, Eugenia ;
Lara, Enrique ;
Manel Diaz, Joan .
TRANSPLANTATION, 2020, 104 (01) :176-183
[5]   Kidney Transplant Outcomes in Elderly Population: A Systematic Review and Meta-analysis [J].
Artiles, Alberto ;
Dominguez, Ana ;
Subiela, Jose Daniel ;
Boissier, Romain ;
Campi, Riccardo ;
Prudhomme, Thommas ;
Pecoraro, Alessio ;
Breda, Alberto ;
Burgos, Francisco Javier ;
Territo, Angelo ;
Hevia, Vital .
EUROPEAN UROLOGY OPEN SCIENCE, 2023, 51 :13-25
[6]   Posttransplant lymphoproliferative disorders after renal transplantation in the United States in era of modern immunosuppression [J].
Caillard, S ;
Dharnidharka, V ;
Agodoa, L ;
Bohen, E ;
Abbott, K .
TRANSPLANTATION, 2005, 80 (09) :1233-1243
[7]   Age Disparities in Access to First and Repeat Kidney Transplantation [J].
Chen, Yusi ;
Churilla, Bryce ;
Ahn, JiYoon B. ;
Quint, Evelien E. ;
Sandal, Shaifali ;
Musunuru, Amrusha ;
Pol, Robert A. ;
Hladek, Melissa D. ;
Crews, Deidra C. ;
Segev, Dorry L. ;
McAdams-DeMarco, Mara .
TRANSPLANTATION, 2024, 108 (04) :845-853
[8]  
Dieplinger Georg, 2013, Clin Transpl, P1
[9]   Kidney Transplant Outcomes in elderly Recipients: An Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry Study [J].
Doucet, Brian Percy ;
Cho, Yeoungjee ;
Campbell, Scott Bryan ;
Johnson, David Wayne ;
Hawley, Carmel Mary ;
Teixeira-Pinto, Armando Rogerio Martins ;
Isbel, Nicole Maree .
TRANSPLANTATION PROCEEDINGS, 2021, 53 (06) :1915-1926
[10]   Maximizing opportunities for kidney transplantation in older adults [J].
Fleetwood, Vidya A. ;
Caliskan, Yasar ;
Abu Al Rub, Fadee ;
Axelrod, David ;
Lentine, Krista L. .
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2023, 32 (02) :204-211