Phenotyping exercise limitation of patients with Interstitial Fibrosing Lung Disease: the importance of exercise hemodynamics

被引：0

作者：

Panagiotidou, E. ^{[1
,4
]}

Boutou, A. ^{[2
]}

Fouka, E. ^{[3
]}

Papakosta, D. ^{[3
]}

Chatzopoulos, E. ^{[1
]}

Sourla, E. ^{[1
]}

Markopoulou, A. ^{[2
]}

Kioumis, I. ^{[3
]}

Stanopoulos, I. ^{[3
]}

Pitsiou, G. ^{[3
]}

机构：

[1] Aristotle Univ Thessaloniki, Gen Hosp Thessaloniki G Papanikolaou, Resp Failure Clin, Thessaloniki, Greece

[2] Gen Hosp G Papanikolaou, Dept Resp Med, Thessaloniki, Greece

[3] Aristotle Univ Thessaloniki, Univ Dept Resp Med, Gen Hosp Thessaloniki G Papanikolaou, Thessaloniki, Greece

[4] 24 N Plastira Str, Thessaloniki 54250, Greece

来源：

PULMONOLOGY | 2024年 / 30卷 / 02期

关键词：

Interstitial fibrosing lung disease; Exercise; Pulmonary hypertension; Hemodynamics pul- monary vascular compliance; Left-heart dysfunction; IDIOPATHIC PULMONARY-FIBROSIS; ARTERIAL-HYPERTENSION; SYSTEMIC-SCLEROSIS; PRESSURE; DIAGNOSIS; ECHOCARDIOGRAPHY; CLASSIFICATION; CRITERIA; FAILURE; SOCIETY;

D O I：

10.1016/j.pulmoe.2022.03.012

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Introduction and objective: Left-heart dysfunction and pulmonary vasculopathy are increasingly recognized as contributing factors of exercise capacity limitation in interstitial fibrosing lung disease (IFLD). Moreover, the clinical significance of exercise pulmonary hypertension (ePH) in pulmonary and cardiac diseases has been documented, representing a risk factor for decreased exercise capacity and survival, progression to resting pulmonary hypertension (PH) and overall clinical worsening. We conducted a prospective study aiming at: (a) assessing the prevalence of PH and ePH in a cohort of 40 functionally limited patients with IFLD, (b) determining the post-capillary (postC) or pre-capillary (preC) etiology of either PH or ePH in this cohort, and (c) examining the correlations between invasively and non-invasively measured exercise variables among hemodynamic groups.

引用

页码：104 / 112

页数：9

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