A Zn-Al-Zr layered double hydroxide/graphene oxide nanocomposite enables rapid photocatalytic removal of kanamycin-resistance bacteria and genes via nano-confinement effects

被引：4

作者：

Yu, Miao ^{[1
,2
]}

Liu, Dawei ^{[1
,2
]}

Wang, Lichao ^{[3
]}

Xia, Jing ^{[4
,5
]}

Ren, Jianhui ^{[1
,2
]}

Fan, Yuqiu ^{[1
,2
]}

Zhu, Xiaofeng ^{[1
,2
]}

Wang, Jun ^{[1
,2
]}

Xiong, Kun ^{[1
,2
]}

机构：

[1] Southwest Univ Sci & Technol, State Key Lab Environm Friendly Energy Mat, Mianyang 621010, Sichuan, Peoples R China

[2] Southwest Univ Sci & Technol, Sch Mat & Chem, Mianyang 621010, Sichuan, Peoples R China

[3] Southwest Univ Sci & Technol, Sch Life Sci & Engn, Mianyang 621010, Sichuan, Peoples R China

[4] Sichuan Agr Univ, Coll Vet Med, Chengdu 611130, Sichuan, Peoples R China

[5] Sichuan Agr Univ, Key Lab Agr Bioinformat, Minist Educ, Chengdu 611130, Sichuan, Peoples R China

来源：

APPLIED CATALYSIS B-ENVIRONMENT AND ENERGY | 2024年 / 350卷

基金：

中国国家自然科学基金;

关键词：

Nano-confinement Effects; Antibiotic-resistance; Photocatalysis; Differential Proteomics; Wastewater Treatment; GRAPHENE OXIDE; DEGRADATION; COMPOSITES;

D O I：

10.1016/j.apcatb.2024.123922

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

For efficient removal of the antibiotic-resistance bacteria and antibiotic-resistance genes, zirconium-doped zincaluminum layered double hydroxide/graphene oxide (Zn-Al-Zr LDHs/GO) nanocomposite has been developed. The Zn-Al-Zr LDHs/GO shows outstanding photocatalytic sterilization, inactivating kanamycin-resistance E. coli (6.53 log10 CFU/mL) under the full-wavelength light irradiation within 50 minutes. Owing to the 1O2 formation, it greatly disrupts the respiratory chain of the kanamycin-resistance E. coli, thereby leading to a declined yield of adenosine triphosphate, down-regulated expressions of the DNA ligase and polymerase proteins, as well as completely inhibited expressions of the DNA repair proteins. Meanwhile, the strong adsorption capability of the Zn-Al-Zr LDHs/GO towards phosphorus endows it with special nano-confinement effects for ARGs. It results in significantly enriched local concentration of the kanamycin-resistance genes on the Zn-Al-Zr LDHs/GO, consequently enhanced removal ability towards the kanamycin-resistance genes (4.70 log10 copies/mL in 3 hours). This work provides a new strategy for effectively removing the ARB and ARGs.

引用

页数：9