Secondary metabolites in topical infectious diseases and nanomedicine applications

被引：0

作者：

Sahoo, Ankit ^{[1
]}

Dwivedi, Khusbu ^{[2
]}

Almalki, Waleed H. ^{[3
]}

Mandal, Ashok Kumar ^{[4
]}

Alhamyani, Abdurrahman ^{[5
]}

Afzal, Obaid ^{[6
]}

Alfawaz Altamimi, Abdulmalik Saleh ^{[6
]}

Alruwaili, Nabil K. ^{[7
]}

Yadav, Pradip Kumar ^{[8
]}

Barkat, Md Abul ^{[9
]}

Singh, Tanuja ^{[10
]}

Rahman, Mahfoozur ^{[11
]}

机构：

[1] JS Univ, Coll Pharm, Firozabad 283135, Utta Pradesh, India

[2] Shambhunath Inst Pharm, Dept Pharmaceut, Prayagraj 211015, Uttar Pradesh, India

[3] Umm Al Qura Univ, Coll Pharm, Dept Pharmacol & Toxicol, Mecca 21955, Saudi Arabia

[4] Univ Malaya, Fac Med, Dept Pharmacol, Kuala Lumpur 50603, Malaysia

[5] Al Baha Univ, Fac Clin Pharm, Pharmaceut Chem Dept, Alaqiq 657797738, Saudi Arabia

[6] Prince Sattam Bin Abdulaziz Univ, Coll Pharm, Dept Pharmaceut Chem, Alkharj 11942, Saudi Arabia

[7] Jouf Univ, Coll Pharm, Dept Pharmaceut, Sakakah, Saudi Arabia

[8] Dibrugarh Univ, Dept Pharmaceut Sci, Dibrugarh 786004, Assam, India

[9] Univ Hafr Al Batin, Coll Pharm, Dept Pharmaceut, Al Batin 39524, Saudi Arabia

[10] Jamia Millia Islamia, Ctr Interdisciplinary Res Basic Sci, New Delhi 10025, India

[11] Sam Higginbottom Univ Agr Technol & Sci, Shalom Inst Hlth & Allied Sci, Dept Pharmaceut Sci, Allahabad 211007, Uttar Pradesh, India

来源：

NANOMEDICINE | 2024年 / 19卷 / 13期

关键词：

bacteria; fungi; nanomedicine; nanotoxicology; secondary metabolites; skin; topical infection; virus; DRUG-DELIVERY SYSTEMS; COATED GOLD NANOPARTICLES; SOLID LIPID NANOPARTICLES; HUMAN SKIN; ANTIMICROBIAL ACTIVITY; ANTIBACTERIAL; DESIGN; NANOMATERIALS; PLEUROCIDIN; TOXICITY;

D O I：

10.2217/nnm-2024-0017

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Topical infection affects nearly one-third of the world's population; it may result from poor sanitation, hygienic conditions and crowded living and working conditions that accelerate the spread of topical infectious diseases. The problems associated with the anti-infective agents are drug resistance and long-term therapy. Secondary metabolites are obtained from plants, microorganisms and animals, but they are metabolized inside the human body. The integration of nanotechnology into secondary metabolites is gaining attention due to their interaction at the subatomic and skin-tissue levels. Hydrogel, liposomes, lipidic nanoparticles, polymeric nanoparticles and metallic nanoparticles are the most suitable carriers for secondary metabolite delivery. Therefore, the present review article extensively discusses the topical applications of nanomedicines for the effective delivery of secondary metabolites.

引用

页码：1191 / 1215

页数：25

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