Research Progress on Anticancer Drugs of Rare Earth Complexes

被引:0
作者
Ji Y. [1 ,2 ]
Gao Y. [2 ]
Chen J. [2 ]
Yang Z. [2 ]
Zhang Z. [2 ]
Li H. [2 ]
Zeng Z. [2 ]
机构
[1] Laboratory Animal Science and Technology Center, Jiangxi University of Traditional Chinese Medicine, Nanchang
[2] Research Center for Differention and Development of TCM Basic Theory, Jiangxi Province Key Laboratory of TCM Etiopathogenisis, Jiangxi University of Traditional Chinese Medicine, Nanchang
来源
Zhongguo Xitu Xuebao/Journal of the Chinese Rare Earth Society | 2021年 / 39卷 / 02期
关键词
Anticancer mechanism; Antitumor activity; Rare earth complex;
D O I
10.11785/S1000-4343.20210201
中图分类号
学科分类号
摘要
Rare earth complexes can be formed by rare earth and ligand under certain conditions, and most rare earth complexes have the functions of rare earth and ligand. Due to the antitumor effect of rare earth, rare earth complexes also have antitumor activity, and it was found that their antitumor activity is significantly better than that of rare earth or ligands. Experiments showed that the human body can absorb trace amounts of rare earth elements, resulting in harmful toxicity or side effects. Therefore, how to develop high efficiency and low toxicity rare earth complex anticancer drugs is the main research goal. In this paper, the rare earth complexes that have been studied in recent years and possess anti-tumor activity and their anti-tumor activity mechanism are summarized, so as to provide reference for the subsequent studies on anticancer drugs of rare earth complexes. © 2021, Editorial Office of Journal of the Chinese Society of Rare Earths. All right reserved.
引用
收藏
页码:197 / 205
页数:8
相关论文
共 56 条
[1]  
Coleman M P., Cancer survival: global surveillance will stimulate health policy and improve equity, Lancet, 383, 9916, (2014)
[2]  
Anghileri L J., On the antitumor activity of gallium and lanthanides, Arzneim. Forsch, 25, 5, (1975)
[3]  
Phuong H T, Huong T T, Vinh L T, Khuyen H T, Thao D T, Huong N T, Lien P T, Minh L Q., Synthesis and characterization of NaYF<sub>4</sub>: Yb<sup>3+</sup>, Er<sup>3+</sup>@silica-N=folic acid nanocomplex for bioimaginable detecting MCF-7 breast cancer cells, J. Rare Earths, 37, 11, (2019)
[4]  
Hosny N M, Sherif Y E., Anti-inflammatory activity of (2E,15E)-2-[1-(2-aminophenyl)ethylidineamino]-N'-[1-(2-aminophenyl)ethylidene]benzoic acid hydrazide (AEBH) and some of its nanoparticles rare earth complexes, Monatsh. Chem, 147, 11, (2016)
[5]  
Chen Z H, Yin G B., Suitability of a rare earth organic light conversion agent of Eu(III) complex to improve ultraviolet protection properties of cotton fabrics [J], Text. Res. J, 80, 18, (2010)
[6]  
Yu L P, Zhang X, Wei D X, Wu Q, Jiang X R, Chen G Q., Highly efficient fluorescent material based on rare-earth-modified polyhydroxyalkanoates, Biomacromolecules, 20, 9, (2019)
[7]  
Puchalska M, Mrozinski J, Legendziewicz J., Magnetic studies of lanthanide complexes with amino acids, J. Alloy Compd, 451, 1-2, (2008)
[8]  
Zhang H, Feng J, Zhu W F, Liu C Q, Xu S Q, Shao P P, Wu D S, Yang W J, Gu J G., Chronic toxicity of rare-earth elements on Human beings [J], Biol. Trace. Elem. Res, 73, 1, (2000)
[9]  
Xing Z H, Cheng M C., Recent advances in pharmacological activity of rare earth salts and its complexes, Journal of the Chinese Society of Rare Earths, 37, 3, (2019)
[10]  
Taha M, Khan I, Coutinho J A., Complexation and molecular modeling studies of europium(III)-gallic acid-amino acid complexes, J. Inorg. Biochem, 157, (2016)