Case Study of Atypical Fibroxanthoma: Presentation and Management

被引:0
作者
Woodson, Johnnie [1 ]
Baha, Alexander [1 ]
Verma, Nikita [1 ]
机构
[1] Chaparral Med Grp, Dermatol, Rancho Cucamonga, CA 91730 USA
关键词
squamous cells carcinoma; sun exposure; skin papule; cutaneous malignancy; immunohistology; mohs surgery; ckae3; vimentin; spindle-shaped cells; atypical fibroxanthoma (afx);
D O I
10.7759/cureus.55094
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Atypical fibroxanthoma (AFX) is a rare spindle cell proliferation arising from significant sun exposure. AFX often appears as a red papule, typically found in the head and neck region of elderly patients. Since there is no specificity in immunohistology, various stains differentiate AFX from other skin cancers. The stains include cluster of differentiation 68 (CD68), cluster of differentiation 163 (CD163), vimentin, cytokeratin epithelial (CKAE), and melanin. While local recurrence is common, AFX rarely metastasizes. Thus, the treatment options are complete surgical excision or micrographically oriented histographic surgery.
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页数:11
相关论文
共 8 条
[1]  
[Anonymous], 2023, Fibrous, fibrohistiocytic and myofibroblastic neoplasms: atypical fibroxanthoma
[2]   Atypical Fibroxanthoma Within a Melanoma: A Case Report [J].
Bhatti, Dujanah S. ;
Raj, Dharshanan Raj Sela ;
Khan, Muhammad Adil A. ;
Ahmad, Raheel ;
Ul Ain, Nur ;
Smith, Louise J. .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (12)
[3]  
Inskip Mike, 2014, Dermatol Pract Concept, V4, P77, DOI 10.5826/dpc.0402a16
[4]  
Kolb L, 2024, Atypical fibroxanthoma. StatPearls
[5]   Atypical Fibroxanthoma: Outcomes from a Large Single Institution Series [J].
McClure, Erin ;
Carr, Michael J. ;
Patel, Ayushi ;
Naqvi, Syed Mahrukh Hussnain ;
Kim, Youngchul ;
Harrington, Michael ;
Cruse, Wayne ;
Gonzalez, Ricardo J. ;
Sondak, Vernon K. ;
Sarnaik, Amod A. ;
Messina, Jane L. ;
Zager, Jonathan S. .
CANCER CONTROL, 2023, 30
[6]  
Ming YU, 2023, Foot Ankle Surg., V3, DOI [10.1016/j.fastrc.2023.100319, DOI 10.1016/J.FASTRC.2023.100319]
[7]   Two friends with eroded nodules on the ears: atypical fibroxanthoma case report [J].
Pesapane, Filippo ;
Nazzaro, Gianluca ;
Lunardon, Luisa ;
Coggi, Antonella ;
Gianotti, Raffaele .
ANAIS BRASILEIROS DE DERMATOLOGIA, 2015, 90 (04) :577-579
[8]  
Sidiropoulou Polytimi, 2020, J Clin Aesthet Dermatol, V13, P53