Clinical translation of wireless soft robotic medical devices

被引：12
作者：
Wang, Tianlu [1 ,2 ]
Wu, Yingdan [1 ,3 ]
Yildiz, Erdost [1 ]
Kanyas, Selin [1 ]
Sitti, Metin [1 ,4 ,5 ]
机构：
[1] Max Planck Inst Intelligent Syst, Phys Intelligence Dept, Stuttgart, Germany
[2] Univ Hawaii Manoa, Dept Mech Engn, Honolulu, HI USA
[3] Harbin Inst Technol, State Key Lab Robot & Syst, Harbin, Peoples R China
[4] Koc Univ, Sch Med, Istanbul, Turkiye
[5] Koc Univ, Coll Engn, Istanbul, Turkiye
来源：
NATURE REVIEWS BIOENGINEERING | 2024年 / 2卷 / 06期
基金：
欧洲研究理事会;
关键词：
FABRICATION; DESIGN; BIODISTRIBUTION; ASSOCIATION; TOXICOLOGY; HYDROGELS; TOXICITY; ANTIBODY; IMPLANT; RECALLS;
D O I：
10.1038/s44222-024-00156-7
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Small-scale wireless soft robotics can be designed as implantable, interventional or wearable devices for various biomedical applications. Their flexibility, dexterity, adaptability and safe interactions with biological environments make them promising candidates for enabling precise and remote healthcare and disease diagnosis. However, the clinical translation of wireless soft robotic medical devices remains challenging. In this Review, we provide a comprehensive overview of the robotic technologies, the navigation methods, the dexterous functions and the translational challenges of wireless soft robotic medical devices. We first discuss safety and biocompatibility from a biological and technical perspective and then examine navigation methods for overcoming biological barriers for delivery, mobility and retrieval, highlighting dexterous medical functions at small scales. Finally, we identify key product development challenges, as well as the regulatory and ethical considerations that should be addressed to enable the clinical translation of wireless soft robotic medical devices.
引用
收藏
页码：470 / 485
页数：16
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